6268-58-2Relevant academic research and scientific papers
Tandem Oxidative Ring-Opening/Cyclization Reaction in Seconds in Open Atmosphere for the Synthesis of 1-Tetralones in Water-Acetonitrile
Fang, Jingxian,Li, Lesong,Yang, Chu,Chen, Jinping,Deng, Guo-Jun,Gong, Hang
supporting information, (2018/11/23)
A mild and practical tandem oxidative ring-opening/cyclization reaction mediated by Ce4+ for the synthesis of 1-tetralones is presented. This rapid transformation was completed within 30 s and conducted in an open reactor at 0 °C in a water-acetonitrile mixture. Various cyclobutanol derivatives are transformed into desired products in good to high yields, and this reaction can be easily scaled up to the gram scale.
Tandem Oxidative Ring-Opening/Cyclization Reaction in Seconds in Open Atmosphere for the Synthesis of 1-Tetralones in Water-Acetonitrile
Fang, Jingxian,Li, Lesong,Yang, Chu,Chen, Jinping,Deng, Guo-Jun,Gong, Hang
supporting information, p. 7308 - 7311 (2018/11/25)
A mild and practical tandem oxidative ring-opening/cyclization reaction mediated by Ce4+ for the synthesis of 1-tetralones is presented. This rapid transformation was completed within 30 s and conducted in an open reactor at 0 °C in a water-acetonitrile mixture. Various cyclobutanol derivatives are transformed into desired products in good to high yields, and this reaction can be easily scaled up to the gram scale.
C–C Bond Formation by Oxidative Ring-Opening Homocoupling of Cyclobutanols
Zeng, Huiying,Pan, Pan,Chen, Jinping,Gong, Hang,Li, Chao-Jun
supporting information, p. 1070 - 1073 (2017/02/23)
The formation of a C(sp3)–C(sp3) bond by oxidative ring-opening homocoupling of cyclobutanols was explored. A broad scope of 1-substituted cyclobutanols were transformed into C(sp3)–C(sp3) bond-formation products by oxidative ring opening in good to high yields under exceptionally mild conditions in an open flask in just 30 s.
Reactivities of mixed organozinc and mixed organocopper reagents, 2. Selective n-alkyl transfer in tri-n-butylphosphine-catalyzed acylation of n-alkyl phenylzincs; an atom economic synthesis of n-alkyl aryl ketones
Erdik, Ender,Pekel, ?zgen ?mür
experimental part, p. 1501 - 1503 (2009/06/21)
Tri-n-butylphosphine-catalyzed acylation of mixed n-alkyl phenylzincs with aromatic acyl halides in THF is efficient in selective transfer of n-alkyl groups to produce n-alkyl aryl ketones in good yields. This route provides an atom economic organocatalyzed alternative to transition metal-catalyzed acylation of di-n-alkylzincs.
Nucleophilic benzoylation using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion. Oxidative decarboxylation of α-hydroxyacids
Blay, Gonzalo,Fernández, Isabel,Formentin, Pilar,Monje, Belén,Pedro, José R,Ruiz, Rafael
, p. 1075 - 1081 (2007/10/03)
The synthesis of alkyl aryl ketones using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion is reported (Umpolung). The methodology involves alkylation of methyl mandelate, hydrolysis of the ester group and oxidative decarboxylation of the resulting α-hydroxyacids. The last step is carried out in a catalytic aerobic way using a Co(III) complex in the presence of pivalaldehyde under very mild and advantageous conditions. The procedure is also applied to methyl mandelates substituted on the aromatic ring.
Effects of methylene chains on photoreactions of diphenylalkanediones and phenylalkenones
Nakamura, Mitsunobu,Miki, Masamichi,Majima, Tetsuro
, p. 415 - 420 (2007/10/03)
Upon conventional UV-irradiation of I,ω-diphenylalkane-1,ω-dione (PhC(O)-(CH2)n-C(O)Ph, n= 5, 6, 7, 8, and 10) in acetonitrile using a medium-pressure Hg lamp, an intramolecular γ-hydrogen abstraction of the triplet ketone (type II p
Lewis Acid-Promoted Disproportionation Reaction of Aromatic Vinyl Ethers and Acetals and Its Application to the Synthesis of Paracotoin
Gong, Young Dae,Tanaka, Hiroko,Iwasawa, Nobuharu,Narasaka, Koichi
, p. 2181 - 2185 (2007/10/03)
Aromatic vinyl ethers and acetals underwent a novel addition-fragmentation reaction affording olefins and esters in the presence of a Lewis acid. This reaction was applied to intramolecular cyclization reaction, giving five or six membered ring compounds in good yields. Paracotoin, an intermediate in the biosynthesis of shikimic acid, was synthesized using this cyclization reaction as the key step.
One-step synthesis of 1,n-dicarbonyl compounds from carboxylic acid derivatives and di-Grignard reagents in the presence of transition metal catalysts
Babudri, F.,D'Ettole, A.,Fiandanese, V.,Marchese, G.,Naso, F.
, p. 53 - 58 (2007/10/02)
The transition metal catalyzed cross-coupling reaction of alkane di-Grignard reagents with carboxylic acid derivatives provides a convenient one-step synthesis of symmetrical 1,n-diketones (n8) and long-chain dicarboxylic thiol esters.
A Convenient Synthesis of Diketones via Alkylation of Alkyl Methyl Ketone Dimethylhydrazones
Yamashita, Masakazu,Matsumiya, Kaoru,Morimoto, Hiroko,Suemitsu, Rikisaku
, p. 1668 - 1670 (2007/10/02)
Symmetrical diketones were prepared by the reaction of the lithium salts of alkyl methyl metone dimethylhydrazones with dibromoalkanes.
