6268-58-2Relevant articles and documents
Tandem Oxidative Ring-Opening/Cyclization Reaction in Seconds in Open Atmosphere for the Synthesis of 1-Tetralones in Water-Acetonitrile
Fang, Jingxian,Li, Lesong,Yang, Chu,Chen, Jinping,Deng, Guo-Jun,Gong, Hang
supporting information, (2018/11/23)
A mild and practical tandem oxidative ring-opening/cyclization reaction mediated by Ce4+ for the synthesis of 1-tetralones is presented. This rapid transformation was completed within 30 s and conducted in an open reactor at 0 °C in a water-acetonitrile mixture. Various cyclobutanol derivatives are transformed into desired products in good to high yields, and this reaction can be easily scaled up to the gram scale.
C–C Bond Formation by Oxidative Ring-Opening Homocoupling of Cyclobutanols
Zeng, Huiying,Pan, Pan,Chen, Jinping,Gong, Hang,Li, Chao-Jun
supporting information, p. 1070 - 1073 (2017/02/23)
The formation of a C(sp3)–C(sp3) bond by oxidative ring-opening homocoupling of cyclobutanols was explored. A broad scope of 1-substituted cyclobutanols were transformed into C(sp3)–C(sp3) bond-formation products by oxidative ring opening in good to high yields under exceptionally mild conditions in an open flask in just 30 s.
Nucleophilic benzoylation using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion. Oxidative decarboxylation of α-hydroxyacids
Blay, Gonzalo,Fernández, Isabel,Formentin, Pilar,Monje, Belén,Pedro, José R,Ruiz, Rafael
, p. 1075 - 1081 (2007/10/03)
The synthesis of alkyl aryl ketones using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion is reported (Umpolung). The methodology involves alkylation of methyl mandelate, hydrolysis of the ester group and oxidative decarboxylation of the resulting α-hydroxyacids. The last step is carried out in a catalytic aerobic way using a Co(III) complex in the presence of pivalaldehyde under very mild and advantageous conditions. The procedure is also applied to methyl mandelates substituted on the aromatic ring.
