627-04-3

Basic information

• Product Name: (ETHYLTHIO)ACETIC ACID
• Synonyms: (ETHYLTHIO)ACETIC ACID;(ethylthio)-aceticaci;S-Ethylthioglycolic acid;2-(Ethylthio)acetic acid;2-ethylsulfanylacetic acid;2-ethylsulfanylethanoic acid
• CAS NO: 627-04-3
• Molecular Formula: C₄H₈O₂S
• Molecular Weight: 120.17
• EINECS: 210-979-8
• Mol File: 627-04-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: -8.5℃
• Boiling Point: 117-118°C 11mm
• Flash Point: 117-118°C/11mm
• Appearance: /liquid
• Density: 1.164±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0254mmHg at 25°C
• Refractive Index: 1.4860
• PKA: 3.84±0.10(Predicted)
• BRN: 1743038
• CAS DataBase Reference: (ETHYLTHIO)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (ETHYLTHIO)ACETIC ACID(627-04-3)
• EPA Substance Registry System: (ETHYLTHIO)ACETIC ACID(627-04-3)

Safety Data

• Hazard Codes: Xi
• Statements: 34-36
• Safety Statements: 26-36/37/39-45
• RIDADR: 3265
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 627-04-3(Hazardous Substances Data)

Usage

General Description

(Ethylthio)acetic Acid, also known by its IUPAC name as Ethylthioacetic Acid, is a type of organic compound that belongs to the class of organic compounds known as carboxylic acids. Specifically, it is a carboxylic acid that contains a sulfur atom in its structure. This chemical usually appears as a brown liquid and has a strong, unpleasant odor. It is often used in the production of some pharmaceuticals, agrochemicals, and dyes. Its primary function involves participating in certain chemical reactions where it acts as an excellent nucleophile, a species that donates an electron pair to an electrophile to form a chemical bond, due to the presence of sulfur.

InChI:InChI=1/C4H8O2S/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6)

Upstream product

• 3926-62-3 sodium monochloroacetic acid 
• 811-51-8 sodium thioethylate 
• 74-96-4 ethyl bromide 
• 68-11-1 mercaptoacetic acid 
• 563-17-7 potassium ethyl sulfate 
• 79-11-8 chloroacetic acid 
• 75-08-1 ethanethiol 
• 36638-31-0 1,1,2-tris-ethylsulfanyl-ethene 
• 4841-22-9 (4-chloro-phenoxy)-acetic acid methyl ester 
• 105-39-5 chloroacetic acid ethyl ester 
• 79-14-1 glycolic Acid 
• 7732-18-5 water 
• 75-03-6 ethyl iodide 
• 1071-37-0 2-ethylisothiourea hydrobromide 

Downstream Products

• 30506-11-7 Dibromomethyl ethyl sulfon 
• 57830-38-3 ethanesulfinyl-acetic acid 
• 58992-39-5 (C₆H₅)3Bi(OOCCH₂SC₂H₅)2 
• 636-70-4 triethylamine hydrobromide 
• 1444176-48-0 N-[[4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]-2-methylphenyl]methyl]-N-ethyl-2-ethylsulfanylacetamide 
• 1132699-40-1 N-[4-[5-[3,5-bis(trifluoromethyl) phenyl]-5-trifluoromethyl-4,5-dihydroisoxazole-3-yl] phenyl] [cyano] methyl-2-(ethylthio) acetamide 
• 1132700-54-9 N-[2-chloro-4-[5-(3,4,5-trichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazole-3-yl]phenyl]methyl-2-ethylthio-N-methylacetamide 
• 339983-71-0 C₆H₅Pd(P(C₆H₅)3)2OCOCH₂SCH₂CH₃ 
• 22132-08-7 Ethylmercaptoessigsaeure-o-nitro-phenylester 
• 27850-41-5 Phenyl-aethylthioacetat 
• 20600-64-0 methyl ethylsulfenylacetate 
• 60247-87-2 ethylsulfanyl-acetic acid amide 

Relevant articles and documents

HETEROCYCLIC AMIDE COMPOUND

PROBLEM TO BE SOLVED: To provide a heterocyclic amide compound useful as an active ingredient of a herbicide. SOLUTION: The present disclosure provides a heterocyclic amide compound represented by the following formula or a salt thereof. Q-N(R3)-C(=X)-W (Q: a substituted/unsubstituted 1,3,4-oxadiazole, 1,2,5-oxadiazole or the like. W: a substituted/unsubstituted [1,2,4]triazolo[4,3-a]pyridine or the like. X: O, S. R3: H, C1-C6 alkyl or the like). SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

HETEROCYCLIC AMIDO COMPOUND

PROBLEM TO BE SOLVED: To provide a novel pesticide, especially a herbicide. SOLUTION: There are provided a heterocycle amide compound such as 3-isopropyl-N-(5-methyl-1, 3, 4-oxadiazole-2-yl)-5-(trifluoromethyl)-[1, 2, 4]triazolo [4,3-a] pyridine-8-carboxamide (compound No.1-004), 3-isopropyl-N-(5-methyl-1, 3, 4-oxadiazole-2-yl)-5-(methylthio)-[1,2,4] triazolo [4,3-a] pyridine-8-carboxamide (compound No.1-009), and a herbicide containing them. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

3-Thiolated 2-azetidinones: Synthesis and in vitro antibacterial and antifungal activities

A series of 3-thiolated β-lactams were synthesized by [2+2] ketene-imine cycloaddition reaction from S-substituted mercaptoacetic acids and Schiff bases. Then, some of the 3-methylthio β-lactams were converted to 3-(methylsulfinyl) β-lactams and 3-(methylsulfonyl) β-lactams using m-CPBA under different reaction conditions. All the compounds were characterized by spectral data and elemental analyses and were evaluated for their in vitro antibacterial and antifungal activities against pathogenic strains including Staphylococcus aureus (Methicillin resistant strain). The preliminary screening results indicated that some of these compounds demonstrated moderate to very good antibacterial and antifungal activities.