6270-67-3

Usage

Uses

Used in Perfume and Personal Care Products:
Propan-2-yl 2-(propan-2-yloxy)benzoate is used as a fragrance ingredient in perfumes and personal care products for its ability to enhance and prolong the scent of other ingredients in a formulation.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, propan-2-yl 2-(propan-2-yloxy)benzoate is used as a fragrance ingredient to improve the scent of medications and make them more pleasant for patients to use.
Used in Flavoring Industry:
Propan-2-yl 2-(propan-2-yloxy)benzoate is used as a flavoring agent in the food and beverage industry to impart a sweet and floral taste to various products.
However, it is important to note that propan-2-yl 2-(propan-2-yloxy)benzoate has been associated with some health concerns, such as skin irritation and allergic reactions in sensitive individuals. Therefore, it is crucial to use this chemical with caution and adhere to safety guidelines when handling and using it in any application.

Upstream product

• 606-45-1 2-methoxybenzoic acid methyl ester 
• 683-60-3 sodium isopropylate 
• 68-12-2 N,N-dimethyl-formamide 
• 75-26-3 isopropyl bromide 
• 69-72-7 salicylic acid 
• 75-30-9 2-iodo-propane 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 63635-26-7 2-isopropoxybenzoic acid 
• 566162-89-8 C₁₀H₁₂⁽²⁾H₂O₂ 

Relevant academic research and scientific papers

Metal-Free Etherification of Aryl Methyl Ether Derivatives by C-OMe Bond Cleavage

A general and efficient protocol was developed for the synthesis of aryl alkyl ethers through metal-free C-OMe bond cleavage under mild reaction conditions. This process displays a wide scope of methoxyarenes and alcohols, including primary, secondary, and tertiary alcohols, as well as natural products, pharmaceuticals, and biologically active alcohols. DFT calculations and experimental results simultaneously confirm that a potassium ion plays a critical role in the activation of methoxy group via binding with the nitrile and provide support for an SNAr mechanism.

The ortho-substituent effect on the Ag-Catalysed decarboxylation of benzoic acids

A combined experimental and computational investigation on the Ag-catalysed decarboxylation of benzoic acids is reported herein. The present study demonstrates that a substituent at the ortho position exerts dual effects in the decarboxylation event. On one hand, ortho-substituted benzoic acids are inherently destabilised starting materials compared to their meta- And para-substituted counterparts. On the other hand, the presence of an ortho-electron-withdrawing group results in an additional stabilisation of the transition state. The combination of both effects results in an overall reduction of the activation energy barrier associated with the decarboxylation event. Furthermore, the Fujita- Nishioka linear free energy relationship model indicates that steric bulk of the substituent can also exert a negative effect by destabilising the transition state of decarboxylation.

Modulators (inhibitors/ activators) of histone acetyltransferases

Disclosed are compounds of the formulae: and method of using the compounds to treat cancer, AIDS, HIV infection, and asthma.

Pyrolysis of O-Allyl Salicylic Amides and Esters, and Related Compounds: Foemation of Isoindolones and Phthalides

Flash vacuum pyrolysis of O-allyl salicylic alkylamides and alkyl esters gives isoindolones and phthalides, respectively, in low (20-40percent) yield.The mechanism involves generation of the phenoxyl radical, regiospecific hydrogen-atom transfer from the alkylamide (or alkyl ester) group and cyclization.A similar sequence was observed with thiophenoxyl radicals.

Facile alkoxyl exchange of 2-methoxybenzoates via nucleophilic aromatic substitution with sodium alkoxides in dimethylformamide

Methyl 2-methoxybenzoate undergoes facile nuclear-methoxyl displacement by treatment with sodium butexide or isopropoxide in dimethylformamide.