62717-14-0

Basic information

• Product Name: Phenol, 2,3-dichloro-6-(2-propenyl)-
• CAS NO: 62717-14-0
• Molecular Formula: C9H8Cl2O
• Molecular Weight: 203.068
• Mol File: 62717-14-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 2,3-dichloro-6-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,3-dichloro-6-(2-propenyl)-(62717-14-0)
• EPA Substance Registry System: Phenol, 2,3-dichloro-6-(2-propenyl)-(62717-14-0)

Safety Data

• Hazardous Substances Data: 62717-14-0(Hazardous Substances Data)

Upstream product

• 68279-46-9 2,3-dichloro-1-(propenyloxy)benzene 
• 576-24-9 2,3-dichlorophenol 
• 106-95-6 allyl bromide 

Downstream Products

• 62717-15-1 2,3-dichloro-6-(2,3-epoxypropyl)phenol 
• 377741-29-2 2,3-dichloro-6-[1,3]dioxolan-2-ylphenol 
• 43119-53-5 ethyl 2,3-dihydro-1-benzofuran-2-carboxylate 
• 62717-17-3 6,7-dichloro-2,3-dihydro-2-benzofurancarboxylic acid 
• 62717-16-2 6,7-dichloro-2,3-dihydro-2-hydroxymethylbenzofuran 
• 118434-69-8 6,7-dichloro-2--2,3-dihydrobenzofuran 
• 377741-28-1 6-(1-propenyl)-2,3-dichlorophenol 
• 126707-93-5 2,3-Dichloro-6-(2-chloro-3-phenylsulfanyl-propyl)-phenol 
• 126707-94-6 2,3-Dichloro-6-(3-chloro-2-phenylsulfanyl-propyl)-phenol 
• 118434-61-0 6,7-dichloro-2-(phenylthiomethyl)-2,3-dihydrobenzofuran 
• 126707-95-7 7,8-Dichloro-3-phenylsulfanyl-chroman 

Relevant articles and documents

Synthesis of methyl 2,3-dihydro-2-benzofurancarboxylates from o-allylphenols via 2-(phenylthiomethyl)-2,3-dihydrobenzofurans

A method for synthesizing methyl 2,3-dihydro-2-benzofurancarboxylates rom o-allylphenols is described.The reaction of 6allyl-2,3-dichlorophenol (3) with benzenesulfenyl chloride (PhSCl) in acetonitrile gave a mixture of PhSCl -adducts, which was heated in aqueous acetonitrile then with sodium bicarbonate to obtain 6,7-dichloro-2-(phenylmethyl)-2,3-dihydrobenzofuran (6). α-Dichlorination of the phenylthiomethyl group of 6 and subsequent methanolysis gave the methyl ester 5 in high yield.The generality of this synthetic method was examined by the conversion of o-allylphenols 11 having various substituents on the benzene ring into the corresponding methyl ester 23.Cyclization of 11 to sulfides 12 could be achived similerly to the case of 3.However, in the subsequent conversions of 12 to 23, selective α-dichlorination followed by methanolysis could be achived only with 12 substituted with an electron-withdrawing group such as a chloro or nitro group.Keywords - oallylphenils; methyl 2,3-dihydro-2-benzofurancarboxylate; 2-(phenylthiomethyl)-2,3-dihydrobenzofuran; benzenesulfenyl chloride; α-chlorination; methanolysis.

(Acylaryloxy)acetic Acid Diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic Acids, a New Class of Uricosuric Diuretics

The discovery that dihydroethacrynic acid and other (4-acylphenoxy)acetic acids possessed modest but significant uricosuric and diuretic activity prompted our investigation of the related 2,3-dihydro-5-acyl-2-benzofurancarboxylic acids.Synthetic routes to

2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids

2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuri