62717-16-2

Basic information

• Product Name: (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol
• Synonyms: (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol;6,7-dichloro-2,3-dihydro-2-benzofuranmethanol
• CAS NO: 62717-16-2
• Molecular Formula: C₉H₈Cl₂O₂
• Molecular Weight: 219.06462
• Mol File: 62717-16-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol(62717-16-2)
• EPA Substance Registry System: (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol(62717-16-2)

Safety Data

• Hazardous Substances Data: 62717-16-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol is used as a starting material for the synthesis of various pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, (6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol is utilized as a starting material for the synthesis of different agrochemicals, such as pesticides and herbicides. Its chemical properties make it suitable for creating effective and targeted solutions for agricultural needs.
Used in Medicinal Chemistry Research:
(6,7-Dichloro-2,3-dihydrobenzofuran-2-yl)Methanol is employed as a research compound in the field of medicinal chemistry. Its unique structure and reactivity make it an interesting subject for studying the development of new drugs and understanding the underlying mechanisms of various diseases.

Upstream product

• 68279-46-9 2,3-dichloro-1-(propenyloxy)benzene 
• 62717-14-0 2,3-dichloro-6-propenylphenol 
• 576-24-9 2,3-dichlorophenol 
• 62717-15-1 2,3-dichloro-6-(2,3-epoxypropyl)phenol 

Downstream Products

• 62717-22-0 6,7-Dichloro-2,3-dihydro-5(4-methoxybenzoyl)benzofuran-2-carboxylic acid 
• 62717-23-1 6,7-dichloro-2,3-dihydro-5-(phenylacetyl)-2-benzofurancarboxylic acid 
• 90246-52-9 6,7-dichloro-2,3-dihydro-5-benzoylbenzofuran-2-carboxylic acid 
• 43119-53-5 ethyl 2,3-dihydro-1-benzofuran-2-carboxylate 
• 103969-31-9 Acetic acid 5-(benzyl-methyl-sulfamoyl)-6,7-dichloro-2,3-dihydro-benzofuran-2-ylmethyl ester 
• 103969-34-2 Acetic acid 5-benzylsulfamoyl-6,7-dichloro-2,3-dihydro-benzofuran-2-ylmethyl ester 
• 103969-32-0 Acetic acid 6,7-dichloro-5-(methyl-phenyl-sulfamoyl)-2,3-dihydro-benzofuran-2-ylmethyl ester 
• 103969-35-3 Acetic acid 6,7-dichloro-5-phenylsulfamoyl-2,3-dihydro-benzofuran-2-ylmethyl ester 
• 103969-38-6 6,7-Dichloro-2-hydroxymethyl-2,3-dihydro-benzofuran-5-sulfonic acid benzyl-methyl-amide 
• 103969-41-1 6,7-Dichloro-2-hydroxymethyl-2,3-dihydro-benzofuran-5-sulfonic acid benzylamide 
• 103969-39-7 6,7-Dichloro-2-hydroxymethyl-2,3-dihydro-benzofuran-5-sulfonic acid methyl-phenyl-amide 
• 103969-42-2 6,7-Dichloro-2-hydroxymethyl-2,3-dihydro-benzofuran-5-sulfonic acid phenylamide 
• 90247-21-5 2-(acetoxymethyl)-6,7-dichloro-2,3-dihydro-5-(o-fluorobenzoyl)benzofuran 
• 90247-22-6 8-chloro-5,6-dihydro-3-(o-fluorophenyl)furo[3,2-f]-1,2-benzisoxazole-6-methanol 

Relevant articles and documents

α-Adrenoreceptor Reagents. 2. Effects of Modification of the 1,4-Benzodioxan Ring System on α-Adrenoreceptor Activity

Modification of the 1,4-benzodioxan ring present in RX 781094 (1) has not previously been considered.This paper describes a number of analogues of this ring system, including compounds in which one of the oxygen atoms has been replaced by a methylene group and also those in which the ring size has been changed to give, for example, furan and thiophene derivatives.The dihydroxybenzofuranylimidazoline compound 7 is the only analogue possesing presynaptic antagonist potency and selectivity comparable to that of 1.In view of this result, a number of derivatives was prepared to determine the structure-activity relationships within this series.Many derivatives, as well as the parent compound 7, were found to possess presynaptic α2-adrenoreceptor antagonist and postsynaptic α1-adrenoreceptor partial agonist properties.Two of the selective presynaptic antagonists,13 and 14, possess greater potency and selectivity than that possessed by 1.The 5-chloro derivative 25 is twice as potent as 1 after oral administration but only about half as potent when given intravenously.

(Acylaryloxy)acetic Acid Diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic Acids, a New Class of Uricosuric Diuretics

The discovery that dihydroethacrynic acid and other (4-acylphenoxy)acetic acids possessed modest but significant uricosuric and diuretic activity prompted our investigation of the related 2,3-dihydro-5-acyl-2-benzofurancarboxylic acids.Synthetic routes to

5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives

5-[Hydroxy(substituted)methyl]-2,3-dihydrobenzo-furan-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuric and antihypertensive activity.

2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids

2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuri

6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids

6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuric and antihy