6275-02-1Relevant articles and documents
Preparation method and application of O-nitrobenzaldehyde
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Paragraph 0038-0040; 0042-0044, (2020/09/23)
The invention relates to a preparation method of o-nitrobenzaldehyde. The preparation method comprises the following steps: reacting o-nitrobenzyl triphenylphosphonium bromide with the required product o-nitrobenzaldehyde as raw materials to generate 1, 2-bis (o-nitrophenyl) ethylene, and oxidizing with ozone to obtain o-nitrobenzaldehyde. The preparation method has the beneficial effects that only a proper amount of alkali is used for catalysis in a condensation reaction, and an intermediate product 1, 2-bis (o-nitrophenyl) ethylene can be efficiently obtained by catalysis of an alkaline water reaction; and gas-liquid reaction is performed by using a micro-channel reactor to finally obtain the required nitrobenzaldehyde. The method has the advantages of less used raw materials, high reaction yield, less by-products and impurities, simple and feasible purification operation, and convenience for industrial production in workshops. Under the condition that the current chemical engineering environment protection and safety situation is severe, the process route can stably supply the important chemical intermediates of the type in an environment-friendly mode with the extremely high atom utilization rate.
Preparation method of O-nitrobenzaldehyde
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Paragraph 0030-0032; 0034-0036; 0038-0040, (2020/02/14)
The invention relates to a preparation method of o-nitrobenzaldehyde, which comprises the following steps: preparing 1,2-bis(o-nitrophenyl)ethylene by using required products nitrobenzaldehyde and nitrotoluene as raw materials, and carrying out high-efficiency oxidation by using ozone with proper concentration to obtain the final product nitrobenzaldehyde. The preparation method has the beneficialeffects that only a proper amount of alkali is used for catalysis in the condensation reaction, and the intermediate product 1,2-bis(o-nitrophenyl)ethylene can be efficiently obtained by using a conventional solvent to carry out a reaction with water; a gas-liquid reaction then is carried out by using a micro-channel reactor to finally obtain the required nitrobenzaldehyde. The method has the advantages of low use amount of raw materials, high reaction yield, few byproducts and impurities, simple and feasible purification operation and convenience for industrial production in workshops.
Dehydrogenation of nitro derivatives of bibenzyl to corresponding nitro stilbene with dioxygen catalyzed by 2,2,6,6-tetramethylpiperidine-1-oxyl
Lu, Tingting,Lu, Ming
, p. 971 - 975 (2013/02/25)
A simple and effective oxidative dehydrogenation of nitro derivatives of bibenzyl was developed using a mixture of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and metal salts as catalyst under an atmospheric pressure of oxygen. The oxidation of several nitro derivatives of bibenzyl led to corresponding nitro stilbene in good yields, and the yields increased with the increase in the substituted nitro group on the bibenzyl. For example, the aerobic dehydrogenation of 2,2,4,4,6,6-hexanitrobibenzyl in the presence of a catalytic amount of TEMPO with metal salts gave 2,2,4,4,6,6-hexanitrostilbene in 81 % yield and 4,4-dinitrostilbene-2,2-disulfonic acid (75 %) was obtained from 4,4-dinitrobibenzyl-2,2-disulfonic acid. Iranian Chemical Society 2012.
Ionic-liquid-influenced expeditious and stereoselective synthesis of olefins
Bhilare, Sachin V.,Darvatkar, Nitin B.,Deorukhkar, Amol R.,Rasalkar, Meghana S.,Salunkhe, Manikrao M.
, p. 3111 - 3117 (2008/02/12)
1-Butyl-3-methylimidazolium chloroaluminate, [bmim]Cl·.AlCl3 (molar fraction, N=0.67), ionic liquid has been used in combination with metallic Zn for the reductive coupling of carbonyl compounds to synthesize symmetrical olefins, with the Z-isomer formed predominantly. The ionic liquid played a dual role of Lewis acid catalyst and solvent. Copyright Taylor & Francis Group, LLC.
