62750-39-4

Upstream product

• 3588-57-6 Z-DL-Phe-OH 
• 530-62-1 1,1'-carbonyldiimidazole 
• 1161-13-3 N-Cbz-L-Phe 

Downstream Products

• 6372-14-1 (2S)-2-(N-benzyloxycarbonyl)-amino-3-phenyl propanol 
• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 1013917-12-8 (S)-methyl 2-(3-((S)-1-(benzyloxycarbonylamino)-2-phenylethyl)ureido)propanoate 
• 62067-14-5 (S)-benzyl 1-azido-1-oxo-3-phenylpropan-2-ylcarbamate 
• 112037-34-0 Z-Phe-NCO 
• 59830-60-3 benzyl (1S)-(1-formyl-2-phenylethyl)carbamate 
• 6372-14-1 N-((benzyloxy)carbonyl)-L-phenylalaninol 
• 73048-81-4 benzyl (S)-(1-(hydroxyamino)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 114744-85-3 [(S)-1-(methoxy-methyl-carbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester 
• 1231713-01-1 Z-L-Phe-O-tetraethylene glycol-monooctylether 
• 65985-76-4 methyl (S)-4-(((benzyloxy)carbonyl)amino)-3-oxo-5-phenylpentanoate 

Relevant academic research and scientific papers

N-carbamate protected amino acid derived guanidine organocatalysts

We report the preparation of a range of N-protected amino acid derived guanidine organocatalysts and their application to the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 26%. Whilst these catalysts gave poo

An Environmentally Sustainable Mechanochemical Route to Hydroxamic Acid Derivatives

An operationally simple, and cost efficient conversion of carboxylic acids into hydroxamic acid derivatives via a high-energy mechanochemical activation is presented. This ball milling methodology was applied to a wide variety of carboxylic acids dramatically improving purification issues associated with this class of molecules, which still remain one of the main bottlenecks of classical methodologies. (Figure presented.).

A rapid and efficient one-pot method for the reduction of N-protected α-amino acids to chiral α-amino aldehydes using CDI/DIBAL-H

N-Protected amino acids can be easily converted into chiral α-amino aldehydes in a one-pot reaction by activation with CDI followed by reduction with DIBAL-H. This method delivers Boc-, Cbz- and Fmoc-protected amino aldehydes from proteinogenic amino acids in very good isolated yields and complete stereointegrity.

Carbonyldiimidazole (CDI) mediated synthesis of Nα- protected amino acid azides: Application to the one-pot preparation of ureidopeptides

Synthesis of Nα-protected amino acyl azides starting from corresponding acids via the carbonyldiimidazole (CDI) activation is described. The protocol is extended for a one-pot preparation of ureido peptides that circumvents the isolation of acy

Size control and compartmentalization in self-assembled nano-structures of a multisegment amphiphile

A "multisegment amphiphile" has been synthesized by covalently connecting two well known building blocks, a gelator and a micelle forming surfactant. Self-assembly results in the formation of compartmentalized nano-object displaying properties inherited f

Decarboxylative Carbon Acylation of Malonates with Aminoacylimidazoles Mediated by Lewis Acids

Various N-protected aminoacylimidazoles undergo decarboxylative carbon acylation with sodium or potassium monomethylmalonate in THF in the presence of MgCl2, CoCl2 or MnCl2 to give dipeptide analogues (3) in 45-82percent isolated yield.Amino ketoester (3e) undergoes intramolecular cyclization induced by diisopropylethylamine and anhydrous magnesium chloride to trisubstituted tetramic acid (4).