6278-95-1

Basic information

• Product Name: alpha-phenylphenylalanine
• Synonyms: 2,3-Diphenylalanine; Alanine, 2,3-diphenyl-; alpha-Phenylphenylalanine; Phenylalanine, alpha-phenyl-
• CAS NO: 6278-95-1
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.2851
• Mol File: 6278-95-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 377.6°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.214g/cm³
• Vapor Pressure: 2.25E-06mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: alpha-phenylphenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-phenylphenylalanine(6278-95-1)
• EPA Substance Registry System: alpha-phenylphenylalanine(6278-95-1)

Safety Data

• Hazardous Substances Data: 6278-95-1(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 73872-14-7 (2S,4'S,5'S)-(+)-2-Amino-N-(2',2'-dimethyl-4'-phenyl-1',3'-dioxan-5'-yl)-2-phenylacetonitril 
• 100-52-7 benzaldehyde 
• 2835-06-5 phenylglycin 
• 84569-96-0 N-(2-Acetoxy-3-methylbutanoyl)phenylglycin 
• 84570-19-4 (6S)-5-Ethoxy-3,6-dihydro-6-isopropyl-3-phenyl-2H-1,4-oxazin-2-on 
• 84570-03-6 ((S)-2-Hydroxy-3-methyl-butyrylamino)-phenyl-acetic acid 
• 84570-10-5 (6S)-6-Isopropyl-3-phenyl-1,4-morpholin-2,5-dion 
• 84570-17-2 (6S)-3,6-Dihydro-6-isopropyl-5-methoxy-3-phenyl-2H-1,4-oxazin-2-on 
• 84570-35-4 (3S,6S)-3-Benzyl-6-tert-butyl-3,6-dihydro-5-methoxy-3-phenyl-2H-1,4-oxazin-2-on 
• 84570-29-6 (3S,6S)-3-Benzyl-3,6-dihydro-6-isopropyl-5-methoxy-3-phenyl-1,4-oxazin-2-on 
• 117470-84-5 2-{[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-amino}-3-phenyl-propionic acid ethyl ester 
• 4927-43-9 5-benzyl-5-phenylimidazolidine-2,4-dione 
• 84570-30-9 (3S,6S)-3-Benzyl-5-ethoxy-3,6-dihydro-6-isopropyl-3-phenyl-2H-1,4-oxazin-2-on 

Relevant articles and documents

Enantioselective Synthesis of α-Quaternary Amino Acids by Alkylation of Deprotonated α-Aminonitriles

A series of α-quaternary arylglycines were prepared in high optical purity (up to 98% ee) by α-alkylation of deprotonated α-aminonitriles derived by the Strecker reaction from (4S,5S)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane. The procedure includes only chromatographic purification of the final products and is devoid of chromatography or crystallization operations on intermediates to raise the optical purity.

Asymmetric syntheses via heterocyclic intermediates. XVI. Enantioselective synthesis of alpha-alkyl-alpha-phenylglycines by alkylation of 3,6-dihydro-3-phenyl-2H-1,4-oxazin-2-ones chirally substituted at C-6

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