6279-52-3Relevant academic research and scientific papers
Copper-Induced Synthesis of Iminiums: Trimethylamine Oxidation or Amine N-Oxide Conversion
Rousselet, Guilhem,Capdevielle, Patrice,Maumy, Michel
, p. 4999 - 5002 (1995)
The ClCuIIOCuIICl reagent as well as the O2/CuIOAc system oxidize trimethylamine 1a into N,N-dimethyliminium 3a, characterized by its phenolic adduct 5a.This reaction appears to be a biomimetic model for laccase or human c
Convenient synthesis of 2-Amino-4H-chromenes from photochemically generated o-quinone methides and malononitrile
Fujiwara, Makoto,Sakamoto, Masanori,Komeyama, Kimihiro,Yoshida, Hiroto,Takaki, Ken
, p. 59 - 66 (2015/01/30)
2-Amino-4H-chromenes were synthesized in moderate to good yields by the reaction of o-quinone methides photochemically generated from o-(dimethylaminomethyl)phenols with malononitrile. This method was applicable to the synthesis of fluorinated chromenes that were difficult to obtain by other methods. In addition, o-(hydroxymethyl)phenols could be used for the reaction in the presence of tertiary amine bases.
Oxidative ortho-amino-methylation of phenols via C-H and C-C bond cleavage
Sun, Wenbo,Lin, Huacan,Zhou, Wenyu,Li, Zigang
, p. 7491 - 7494 (2014/02/14)
Initiated by CCl3Br, phenols undergo efficient ortho-selective oxidative cross dehydrogenative coupling (CDC) with trimethylamine. When tetramethylethylenediamine (TMEDA) is used instead of trimethylamine, oxidative carbon-carbon activation coupling (CAC) could occur to give the same salicylamines together with CDC by-products. These reactions are accelerated by a gold salt.
