62790-89-0

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 576-26-1 2.6-dimethylphenol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 67-56-1 methanol 
• 762-72-1 allyl-trimethyl-silane 

Downstream Products

• 123-56-8 Succinimide 
• 175841-30-2 [2,6-bis(bromomethyl)phenoxy](tert-butyl)dimethylsilane 
• 1417315-93-5 2-((tert-butyldimethylsilyl)methyl)-6-methylphenol 
• 576-26-1 2.6-dimethylphenol 
• 62791-09-7 tert-Butyl-(2,6-dimethyl-cyclohexa-1,4-dienyloxy)-dimethyl-silane 

Relevant academic research and scientific papers

Synthesis of oxygen- and sulfur-bridged dirhodium complexes and their use as catalysts in the chemoselective hydrogenation of alkenes

Oxygen-bridged and sulfur-bridged rhodium homobimetallic complexes were synthesized as air-stable crystals by using 2,6-bis(phosphanylmethyl)phenolate and -thiophenolate as the ligands, respectively. The oxygen-bridged dirhodium complex has a symmetrical structure where the carbon atom at the ipso position, oxygen, and two rhodium atoms are located in the same plane. It is thermally stable compared to the sulfur-bridged dirhodium complex and shows catalytic activity for hydrogenation of alkenes with high chemoselectivity.

Immortalizing a transient electrophile for DNA cross-linking

(Chemical Equation Presented) Who wants to live forever? Compounds that act as strong nucleophiles and good leaving groups repeatedly capture and release a transient quinone methide to extend its effective lifetime under aqueous conditions and promote DNA

Synthesis and biological studies of inducible DNA cross-linking agents

(Chemical Equation Presented) Checking the traps: When a phenyl selenide compound such as 1 was oxidized with sodium periodate or irradiated, an ortho-quinone methide intermediate formed and reacted with a DNA duplex by cross-linking. In the crystal structure of a derivative of 1 the biphenyl unit is twisted, and this might explain how 1 can interact effectively with the DNA backbone.

Aryl cation and carbene intermediates in the photodehalogenation of chlorophenols

The photochemistry of 2,6-dimethyl-4-chlorophenol (6) has been studied in methanol and trifluoroethanol (TFE) through product studies and transient absorption spectroscopy. Chloride loss from triplet 6 gave triplet hydroxyphenyl cation 1.4, which equilibrated with triplet oxocyclohexadienylydene 15 within a few tens of nanoseconds; the cation can, however, be selectively trapped by allyltrimethylsilane (kad = 108-109 M -1S-1) to give a phenonium ion and the allylated phenol. In neat alcohols, 14 and 15 are reduced through different mechanisms, namely by hydrogen transfer through radical cation 17 and via phenoxyl radical 16, respectively. The mechanistic rationalization has been substantiated by the parallel study of an O-silylated derivative. The work shows that the chemistry of the highly (but selectively) reactive phenyl cation 14 can not only be discriminated from that of the likewise highly reactive carbene 15, but also exploited for synthetically useful reactions, as in this case with alkenes. Photolysis of electron-donating substituted halobenzcnes may be the method of choice for the mild generation of some classes of phenyl cations.