628-09-1

Basic information

• Product Name: 3-Chloropropyl acetate
• Synonyms: 3-CHLOROPROPYL ACETATE;1-ACETOXY-3-CHLOROPROPANE;3-chloro-1-propanoacetate;3-Chloropropanol acetate;3-chloropropanolacetate;3-Chlorprop-1-ylacetat;-Chloropropylacetate;gamma-Chloropropyl acetate
• CAS NO: 628-09-1
• Molecular Formula: C₅H₉ClO₂
• Molecular Weight: 136.58
• Product Categories: Intermediates of Dyes and Pigments;C2 to C5;Carbonyl Compounds;Esters;API Intermediate
• Mol File: 628-09-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 80-81 °C30 mm Hg(lit.)
• Flash Point: 154 °F
• Appearance: clear colorless liquid
• Density: 1.111 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.32mmHg at 25°C
• Refractive Index: n20/D 1.429(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, DMSO (Slightly), Hexanes (Sparingly), Methanol (Slightly)
• Water Solubility: Soluble in water (partly).
• CAS DataBase Reference: 3-Chloropropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloropropyl acetate(628-09-1)
• EPA Substance Registry System: 3-Chloropropyl acetate(628-09-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 2
• RTECS: UA8944000
• Hazardous Substances Data: 628-09-1(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless liquid

Uses

3-Chloropropyl acetate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agro chemicals, dyestuff.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 203, 1955The Journal of Organic Chemistry, 48, p. 751, 1983 DOI: 10.1021/jo00153a031

General Description

3-Chloropropyl acetate on reaction with strong base yields trimethylene oxide.

InChI:InChI=1/C5H9ClO2/c1-5(7)8-4-2-3-6/h2-4H2,1H3

Upstream product

• 626-68-6 2-methyl-[1,3]dioxane 
• 23277-12-5 tetrahydro-2-methyl-2-furyl hydroperoxide 
• 23277-15-8 2-methyltetrahydrofuran peroxide 
• 509-14-8 tetranitromethane 
• 127-08-2 potassium acetate 
• 64-19-7 acetic acid 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 503-30-0 trimethylene oxide 
• 14091-44-2 4-Iodo-benzoic acid 3-acetoxy-propyl ester 
• 705290-39-7 acetic acid 3-(2-chloro-phenoxy)-propyl ester 
• 78444-68-5 3-p-nitrophenylthio-1-propyl acetate 
• 62116-24-9 3-acetoxypropyl iodide 
• 16332-31-3 (3-acetoxy-propyl)-trimethyl-ammonium; chloride 
• 1023971-10-9 (-)-(R)-2-amino-3-(3-hydroxypropylthio)propionic acid 

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In a medium containing a donor of hydrogen atoms and carbon tetrachloride 2-methyltetrahydrofuran-2-oxyl radicals are consumed in parallel reactions leading to acetopropyl alcohol and 3-chloropropyl acetate.It was shown that the reactivity of the hydrogen donor with respect to 2-methyltetrahydrofuran-2-oxyl radicals can be estimated quantitatively from determination of the paths for the consumption of the radicals.The ratios of the rate constants for the abstraction of a hydrogen atom from organic compounds by 2-methyltetrahydrofuran-2-oxyl radicals to the rate constants for its rearrangement to 3-acetoxypropyl radical were determined.