62838-20-4 Usage
General Description
3-(2-aminoethyl)-2-phenylquinazolin-4(3H)-one is a chemical compound with a quinazolinone core structure. It contains an aminoethyl side chain and a phenyl group. 3-(2-aminoethyl)-2-phenylquinazolin-4(3H)-one has been studied for its potential pharmaceutical applications, including its possible use as an inhibitor of angiogenesis and as an antitumor agent. It has also shown potential for use in the treatment of central nervous system diseases, such as Parkinson's disease and schizophrenia. Additionally, 3-(2-aminoethyl)-2-phenylquinazolin-4(3H)-one has been researched for its potential as a bioactive compound with antibacterial and antifungal properties. Overall, this compound has garnered interest in the fields of medicinal chemistry and drug development due to its diverse and potentially beneficial biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 62838-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,8,3 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 62838-20:
(7*6)+(6*2)+(5*8)+(4*3)+(3*8)+(2*2)+(1*0)=134
134 % 10 = 4
So 62838-20-4 is a valid CAS Registry Number.
62838-20-4Relevant articles and documents
Anti-convulsant potential of quinazolinones
Patel, Harun M.,Noolvi, Malleshappa N.,Shirkhedkar, Atul A.,Kulkarni, Abhijeet D.,Pardeshi, Chandrakantsing V.,Surana, Sanjay J.
, p. 44435 - 44455 (2016/06/09)
A series of novel quinazoline derivatives were synthesized, virtually screened through different filters and evaluated for their anticonvulsant activity against electrically and chemically induced seizures, compared with that of the standard drugs methaqualone and sodium valproate. Compound 48, 3-(2-aminophenyl)-7-chloro-2-phenylquinazolin-4(3H)-one, was found to be the most potent compound of the series accompanied by relatively low neurotoxicity and low toxicity in the median lethal dose test as compared with the reference drugs. The obtained results showed that compounds 12, 48, 49 and 50 could be useful templates for future design, optimization, and investigation to construct more active analogs.
