62856-06-8

Basic information

• Product Name: Benzonitrile, 4-[(4-methylphenyl)ethynyl]-
• CAS NO: 62856-06-8
• Molecular Formula: C16H11N
• Molecular Weight: 217.27
• Mol File: 62856-06-8.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[(4-methylphenyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[(4-methylphenyl)ethynyl]-(62856-06-8)
• EPA Substance Registry System: Benzonitrile, 4-[(4-methylphenyl)ethynyl]-(62856-06-8)

Safety Data

• Hazardous Substances Data: 62856-06-8(Hazardous Substances Data)

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 766-97-2 4-n-methylphenylacetylene 
• 624-31-7 4-tolyl iodide 
• 131356-52-0 2,2-dibromo-1-(4-cyanophenyl)ethene 
• 3032-92-6 4-cyanophenylacetylene 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 873-74-5 4-Aminobenzonitrile 
• 3058-39-7 4-iodobenzonitrile 
• 5720-05-8 4-methylphenylboronic acid 
• 623-00-7 4-bromobenzenecarbonitrile 
• 65085-94-1 4-(2,2-dichlorovinyl)-benzonitrile 
• 126747-14-6 4-cyanophenylboronic acid 
• 157729-39-0 4-(2-bromoethynyl)-benzonitrile 

Downstream Products

• 444169-52-2 2-hydroxyethyl 4-cyanobenzoate 
• 28129-15-9 2-hydroxyethyl 4-methylbenzoate 
• 41425-61-0 4-[(E)-2-(4-Methylphenyl)ethen-1-yl]benzonitrile 

Relevant articles and documents

A facile protocol for copper-free palladium-catalyzed Sonogashira coupling in aqueous media

The combination of a readily available palladium catalyst and an eco-friendly basic aqueous solution of room-temperature ionic liquid, choline hydroxide (ChOH), was used in a facile protocol alternative to the Sonogashira coupling reaction, alkynylation of aryl halides in the absence of a copper cocatalyst and an external base. The dual nature of ChOH to act as a base and a green solvent played a crucial role in the catalytic cycle. The coupling reaction progressed efficiently to form a Csp-Csp2 bond under the identified conditions although the reaction outcome depended significantly on the substrates.

Nickel-Catalyzed Sonogashira C(sp)-C(sp2) Coupling through Visible-Light Sensitization

An efficient method for visible-light-initiated, nickel-catalyzed Sonogashira C(sp)-C(sp2) coupling has been developed via an energy-transfer mode. Thioxanthen-9-one as a photosensitizer could significantly accelerate the arylation of alkynes with a wide

DBU-Mediated Efficient Synthesis of Diaryl Ethynes and Enynes from 1,1-Dibromoalkenes at Room Temperature

The reaction of 1,1-dibromoalkenes and aryl iodides in the presence of DBU and a PdII/CuI catalytic system afforded diaryl alkynes and enynes at ambient temperature. Control experiments demonstrated the essential ligand role of DBU i