628732-48-9

Basic information

• Product Name: 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID
• Synonyms: 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID;5-FLUORO-2,3-DIHYDRO-1H-INDENE-1-CARBOXYLIC ACID;5-Fluoro-indan-1-carboxylic acid
• CAS NO: 628732-48-9
• Molecular Formula: C₁₀H₉FO₂
• Molecular Weight: 180.18
• Mol File: 628732-48-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID(628732-48-9)
• EPA Substance Registry System: 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID(628732-48-9)

Safety Data

• Hazardous Substances Data: 628732-48-9(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-5-fluoro-1H-indene-1-carboxylic acid is a chemical compound with a molecular formula of C10H9FO2. It is a white to off-white solid crystalline powder that is used primarily in the synthesis of pharmaceutical compounds. 2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID is a carboxylic acid derivative of 5-fluoroindene, which has potential biological activity. It is used in the research and development of new drugs, particularly in the field of antiviral and anti-cancer medications. Additionally, it has been studied for its potential role as a building block in the synthesis of various chemical compounds due to its unique molecular structure.

Upstream product

• 505-23-7 1,3 dithiane 
• 700-84-5 5-fluoro-1-indanone 
• 58485-67-9 1-chloro-5-fluoroindane 
• 52085-92-4 5-fluoro-2,3-dihydro-1H-inden-1-ol 
• 64-19-7 acetic acid 
• 915030-25-0 1-cyano-5-fluoroindane 

Downstream Products

• 628732-50-3 (R)-5-fluoro-indan-1-carboxylic acid 
• 628732-49-0 (S)-5-fluoro-indan-1-carboxylic acid 

Relevant articles and documents

2,3-SUBSTITUTED FUSED BICYCLIC PYRIMIDIN-4(3H)-ONES MODULATING THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)

The use of a compound of formula (I): for the manufacture of a medicament for the treatment of conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1, also known as TRPV1).

4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.

4-SUBSTITUTED IMIDAZOLE-2-THIONES AND IMIDAZOL- 2-ONES AS AGONISTS OF THE ALPHA- 2B AND ALPHA-2C ADRENERGIC RECEPTORS

Compounds of Formula (I): where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula (I) are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula (I) where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.