62936-35-0

Upstream product

• 25726-04-9 phenylglyoxylyl chloride 
• 4885-02-3 Dichloromethyl methyl ether 
• 611-73-4 Benzoylformic acid 
• 108-95-2 phenol 
• 721-04-0 2-phenoxy-1-phenylethanone 
• 98-86-2 acetophenone 
• 1574666-21-9 2-phenoxy-1-phenyl-2-((2,2,6,6-tetramethylpiperidin-1-yl)oxy)ethan-1-one 

Downstream Products

• 14377-63-0 1-(phenylglyoxylyl)piperidine 
• 108-95-2 phenol 
• 1361325-94-1 C₂₁H₁₈O₃ 
• 1279018-00-6 C₁₈H₁₂Cl₂O₅ 

Relevant academic research and scientific papers

Carbene-Catalyzed Enantioselective Aromatic N-Nucleophilic Addition of Heteroarenes to Ketones

The aromatic nitrogen atoms of heteroarylaldehydes are activated by carbene catalysts to react with ketone electrophiles. Multi-functionalized cyclic N,O-acetal products are afforded in good to excellent yields and optical purities. Our reaction involves the formation of an unprecedented aza-fulvene-type acylazolium intermediate. A broad range of N-heteroaromatic aldehydes and electron-deficient ketone substrates works effectively in this transformation. Several of the chiral N,O-acetal products afforded through this protocol exhibit excellent antibacterial activities against Ralstonia solanacearum (Rs) and are valuable in the development of novel agrichemicals for plant protection.

Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of α-Iminoesters

An efficient Pd(OAc)2-catalyzed asymmetric hydrogenation of α-iminoesters was realized for the first time at 1 atm hydrogen pressure and room temperature. Pd(OAc)2, a less expensive Pd salt with low toxicity, was found to be the most suitable catalyst precursor rather than Pd(TFA)2 which is usually the catalyst of choice for homogeneous asymmetric hydrogenation. The chiral α-arylglycine fragments are widely found in many chiral products and bioactive molecules.

Copper-Catalyzed Aminoxylation of Different Types of Hydrocarbons with TEMPO: A Concise Route to N-Alkoxyamine Derivatives

An efficient copper(II)/tert-butyl hydroperoxide catalyst system [(Bpy)Cu(II)/TBHP] for the aminoxylation of different types of hydrocarbons under mild and ambient air conditions has been developed to furnish N-alkoxyamine derivatives in good to high yields. Ketones, esters, nitriles, toluene, ethylbenzene, heterocycles, cyclohexene, and cyclohexanes are well compatible in this system and the catalyst loading could be lowered to 0.5 mol%.

Copper-catalyzed α-aminoxylation of ketones with 2,2,6,6- tetramethylpiperidine-1-oxyl (TEMPO)

An efficient copper-catalyzed α-aminoxylation of ketones with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) is presented for the synthesis of 2-aryloxy-1-aryl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)ethanones in moderate to excellent yields. It is notewort

Copper-catalyzed B-H bond insertion reaction: A highly efficient and enantioselective C-B bond-forming reaction with amine-borane and phosphine-borane adducts

A copper-catalyzed B-H bond insertion reaction with amine- and phosphine-borane adducts was realized with high yield and enantioselectivity under mild reaction conditions. The B-H bond insertion reaction provides a new C-B bond-forming methodology and an

Iron-catalyzed ortho-selective functionalization of phenols: A straightforward strategy towards the 2′-hydroxyphenyl-1,2-dione skeleton

An iron-catalyzed ortho-functionalization of phenols was developed. The reactions of simple phenols with α-hydroxy ketones provide a novel and efficient method to construct 2′-hydroxyphenyl-1,2-dione derivatives. An iron-catalyzed ortho-functionalization of phenols was developed. The reactions of simple phenols with α-hydroxy ketonesprovide a novel and efficient method to construct 2′-hydroxyphenyl-1,2-dione derivatives.

Study of enantioselective hydrogenation of bulky esters of phenylglyoxylic acid on Pt-CD and Pt-β-ICN chiral catalysts: Steric effect of ester groups and inversion of enantioselectivity

Enantioselective hydrogenation of seven different esters of phenylglyoxylic acid was investigated by variation of the bulkiness at ester side of the substrates [Ph{single bond}C(O){single bond}C(O)OR, R = Me (l), cyclohexyl (2), adamantyl (3), cis-decahyd

Catalyst for decarbonylation reaction

A catalyst composed of an organic phosphorus compound having a trivalent or pentavalent phosphorus atom and at least one carbon-phosphorus bonding or a combination of the organic phosphorus compound and a halogen atom-containing compound is effective for decarbonylation, that is, for releasing carbon monoxide from a compound containing a moiety of --CO--CO--O-- in its molecular structure.

Catalyst for decarbonylation reaction

A catalyst composed of an organic phosphorus compound having a trivalent or pentavalent phosphorus atom and at least one carbon-phosphorus bonding or a combination of the organic phosphorus compound and a halogen atom-containing compound is effective for decarbonylation, that is, for releasing carbon monoxide from a compound containing a moiety of -CO-CO-O- in its molecular structure.