629645-55-2

Basic information

• Product Name: (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester
• Synonyms: (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester;(4-chloro-2-pyrimidinyl)-Carbamic acid, 1,1-dimethylethyl ester (9CI);(4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl este;TERT-BUTYL (4-CHLOROPYRIMIDIN-2-YL)CARBAMATE
• CAS NO: 629645-55-2
• Molecular Formula: C₉H₁₂ClN₃O₂
• Molecular Weight: 229.66348
• Mol File: 629645-55-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester(629645-55-2)
• EPA Substance Registry System: (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester(629645-55-2)

Safety Data

• Hazardous Substances Data: 629645-55-2(Hazardous Substances Data)

Usage

General Description

(4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester is a chemical compound with the molecular formula C8H11ClN2O2. It is commonly used as a pesticide and herbicide to control various types of weeds, including those in rice paddies, wheat fields, and soybean crops. (4-Chloro-2-pyrimidinyl)carbamic acid 1,1-dimethylethyl ester works by inhibiting the enzyme acetyl-CoA carboxylase, which is essential for fatty acid synthesis in plants, ultimately leading to their death. It is important to handle this chemical with care, as it is toxic to aquatic organisms and may have harmful effects on human health if not properly managed. Additionally, it is important to follow all safety guidelines and regulations when using this compound in agricultural settings.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 629645-53-0 tert-butyl (4-hydroxypyrimidin-2-yl)carbamate 

Downstream Products

• 1464788-84-8 4-chloro-2-amino(bis-carbamate)pyrimidine 
• 629645-60-9 t-butyl 4-(N-(4-bromophenyl)ethanehydrazonoyl)pyrimidin-2-ylcarbamate 
• 629645-59-6 tert-butyl 4-(N-phenylethanehydrazonoyl)pyrimidin-2-ylcarbamate 
• 629645-58-5 tert-butyl [4-acetylpyrimidin-2-yl]carbamate 

Relevant articles and documents

ANTI-ANGIOGENESIS COMPOUND, INTERMEDIATE AND USE THEREOF

Disclosed are an anti-abnormal proliferation of angiogenesis compound represented by formula I, use and intermediate thereof. The compound has good effect against abnormal proliferation of angiogenesis, and the activity of the compound is produced by inhibiting VEGFR2. The compound can be used for treating diseases, such as wet macular degeneration, inflammation, malignant tumor and the like, caused by abnormity of angiogenesis and protein kinases such as VEGFR2, FGFR2 and the like.

Synthesis of 2-(pyrimidin-4-yl)indoles

The synthesis of 2-substituted isomers of the meridianins, a familiy of bioactive indole alkaloids isolated from the tunicate Aplidium meridianum, was undertaken. The synthetic route comprises six steps, with a microwave promoted Fischer cyclization as th