62973-00-6

Basic information

• Product Name: L-Phenylalanine, N-(1,3-dioxobutyl)-, methyl ester
• CAS NO: 62973-00-6
• Molecular Formula: C14H17NO4
• Molecular Weight: 263.293
• Mol File: 62973-00-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-(1,3-dioxobutyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-(1,3-dioxobutyl)-, methyl ester(62973-00-6)
• EPA Substance Registry System: L-Phenylalanine, N-(1,3-dioxobutyl)-, methyl ester(62973-00-6)

Safety Data

• Hazardous Substances Data: 62973-00-6(Hazardous Substances Data)

Upstream product

• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 72324-39-1 5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 674-82-8 4-methyleneoxetan-2-one 
• 186581-53-3 diazomethane 
• 17667-55-9 (3-oxobutanoyl)-L-phenylalanine 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 63-91-2 L-phenylalanine 

Downstream Products

• 129029-32-9 (4S,5S)-5-Benzyl-2-oxo-4-hydroxypyrrolidine 
• 129029-33-0 (4R,5S)-5-Benzyl-4-hydroxy-2-oxopyrrolidine 
• 128892-65-9 (S)-5-Benzyl-4-hydroxy-1,5-dihydro-pyrrol-2-one 
• 2113-89-5 (5S)-3-acetyl-5-benzyl-4-hydroxy-3-pyrroline-2-one 
• 618904-94-2 {[2-(4-methoxyphenyl)-5-methyl-3H-imidazole-4-carbonyl]amino}-phenylacetic acid methyl ester 
• 618904-95-3 2-(4-methoxyphenyl)-5-methyl-3H-imidazole-4-carboxylic acid (1-hydroxymethyl-2-phenylethyl)amide 
• 618904-98-6 2-[(5-methyl-2-p-tolyl-3H-imidazole-4-carbonyl)-amino]-3-phenyl-propionic acid methyl ester 
• 618904-97-5 2-{[2-(4-chloro-phenyl)-5-methyl-3H-imidazole-4-carbonyl]-amino}-3-phenyl-propionic acid methyl ester 
• 618905-08-1 6-benzyl-3-(4-chloro-phenyl)-1-methyl-6,7-dihydro-5H-imidazo[1,5-a]pyrazin-8-one 
• 618904-96-4 6-benzyl-3-(4-methoxyphenyl)-1-methyl-6,7-dihydro-5H-imidazo[1,5-a]pyrazin-8-one 
• 618905-09-2 6-benzyl-1-methyl-3-p-tolyl-6,7-dihydro-5H-imidazo[1,5-a]pyrazin-8-one 

Relevant articles and documents

One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides

Alkylidene acetoacetamides are useful building blocks for the preparation of a number of biologically active derivatives, including dehydro-β-amino-acid-containing peptidomimetics. A one-pot two-step protocol for the preparation of amino-acid-derived unsaturated acetoacetamides has been optimized. The use of microwave activation avoids, or at least decreases, the need for catalysts in both steps. A leucine derivative was selected from the small collection of molecules obtained to be transformed into the corresponding dehydro-β-amino-acid-containing peptidomimetic. It is known that such fragments are able to induce β-turns into peptide sequences, and, due to the presence of the unsaturation, they may represent sites for selective modification and conjugation.

Amic acid derivative as well as preparation method and application thereof

The invention provides an amine acid derivative as well as a preparation method and application thereof. The amine acid derivative has the structure as follows. Herein, R is selected from methyl, methoxy and the like. R1 Selected from C1 - C4 a

Novel Synthetic Approach to 6,7-Dihydro-5H-imidazo[1,5-a]-pyrazin-8-ones

(Matrix presented) A novel route to highly substituted chiral 6,7-dihydro-5H-imidazo[1,5-a]pyrazine-8-ones starting from Meldrum's acid is disclosed. The key features of the methodology are the incorporation of amino esters as a chiral pool and facile mil