7477-28-3

Upstream product

• 85-44-9 phthalic anhydride 
• 112219-63-3 (4-methoxyphenyl)magnesium iodide 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 
• 5449-71-8 methyl 2-(4-methoxybenzoyl)benzoate 
• 6306-97-4 1,3-bis(4-methoxyphenyl)isobenzofuran 
• 7477-32-9 acide (dimethoxy-4'4 diphenylmethyl)-2 benzoique 
• 128709-98-8 1,3-Bis(4-methoxyphenyl)benzothiophen 
• 615-42-9 1,2-Diiodobenzene 
• 100-07-2 4-methoxy-benzoyl chloride 
• 7719-09-7 thionyl chloride 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 162339-29-9 benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester 
• 88-95-9 Phthaloyl dichloride 

Downstream Products

• 5441-28-1 1,4-bis-(4-methoxy-phenyl)-phthalazine 
• 855422-65-0 1,2-bis-(4-hydroxy-benzoyl)-benzene 
• 7477-30-7 1,2-bis-(α-hydroxyimino-4-methoxy-benzyl)-benzene 
• 130443-14-0 1,2-Bis(3-brom-4-methoxybenzoyl)benzol 
• 130443-13-9 1,2-Bis(4-methoxy-3-nitrobenzoyl)benzol 
• 128709-98-8 1,3-Bis(4-methoxyphenyl)benzothiophen 
• 1385794-37-5 C₂₄H₂₂O₂ 
• 860531-53-9 2-methoxy-9-(4-methoxyphenyl)anthracene 
• 6636-09-5 1,2-bis-(α-hydroxy-4-methoxy-benzyl)-benzene 
• 130443-20-8 1,3-Bis-(4-methoxy-3-nitro-phenyl)-benzo[c]thiophene 
• 130443-21-9 1,3-Bis-(3-bromo-4-methoxy-phenyl)-benzo[c]thiophene 

Relevant academic research and scientific papers

1. 4 - (hydroxy-phenyl) II - 2, 3 - naphthyridine derivatives and their synthetic method

The invention discloses 1,4-di(para hydroxybenzene) based-2,3-quinazoline and a synthesis method thereof. In the synthesis method, a Grignard reagent is prepared from para-halogen anisole and magnesium ribbons and is reacted with phthalic anhydride in a tetrahydrofuran/toluene, 2-methyl tetrahydrofuran/toluene, or diethyl ether/toluene mixing solvent to obtain benzol-1,2-di(para-methoxyl)benzophenone; under the solvent of glacial acetic acid or alcohol, the benzol-1,2-bi(para-methoxyl)benzophenone is reacted again with hydrazine hydrate to obtain 2,3-quinazoline1,4-bi-hydroxybenzene; and finally the 2,3-quinazoline1,4-bi-hydroxybenzene is demethylated under the participation of 40 percent of hydrobromic acid by taking the glacial acetic acid as the solvent to obtain the product. The invention provides a new monomer for developing a high-property polymer material with a quinazoline structure. The invention has reasonable and simple selection for a technical route as well as convenience and easy operation and provides a successful synthesis method for the synthesis of the intermediate of the high polymer product technically.

Applications of triphenylpyrylium salt-sensitized electron-transfer photo-oxygenation reactions to the synthesis of benzo-fused 1,4-diaryl-2,3- dioxabicyclo[2.2.2]octanes as new antimalarial cyclic peroxides

Benzo-fused 1,4-diaryl-2,3-dioxabicyclo[2.2.2]octanes 4a-d (4a: Ar = C 6H5, 4b: Ar = p-FC6H4, 4c: Ar = p-MeC6H4, 4d: Ar = p-MeOC6H4) were synthesized by 2,4,6-tripheny

Design of reversible multi-electron redox systems using benzochalcogenophenes containing aryl and/or ferrocenyl fragments

2,3-Disubstituted benzo[b]thiophenes, 1,3-disubstituted benzo[c]thiophenes, and 1,3-disubstituted benzo[c]selenophene have been systematically and selectively synthesized from benzo[b]thiophene or phthaloyl dichloride as a starting material, respectively. Characterization of the molecules was performed by physical and spectroscopic means and X-ray crystallographic analyses. The cyclic voltammograms of the chalcogenophene derivatives containing aryl fragments showed well-defined reversible both anodic and cathodic steps derived from the unusually stable 5π chalcogenophene radical cations and 7π chalcogenophene radical anions. The cyclic voltammograms of the novel chalcogenophene derivatives containing ferrocenyl fragments showed a well-defined reversible cathodic step derived from the unusually stable 7π chalcogenophene radical anions and two distinct reversible anodic steps derived from ferrocenium cations separated from each other by a thiophene-heterocycle. The radical character of several novel 7π chalcogenophene radical anions was measured by ESR spectroscopy.

Ortho-Phenylenedizinc(II) Compounds. Ultrasound-Promoted Synthesis from o-Diiodobenzene and Zinc Powder and Its Synthetic Application

A facile and efficient synthetic procedure of o-phenylenedizinc(II) compound from o-diiodobenzene and zinc powder under the irradiation of ultrasound is reported.The compound was proved to be a unique reagent supplying o-phenylenedianion of high chemoselectivity.Symetrically 1,2-diaryl or diaroyl substiituted benzenes were obtained in good yields by Pd(0)-catalyzed cross-coupling of the compound with aryl halides or acyl halides.

NEW RESULTS ON THE PREPARATION AND REACTIVITY OF BENZOTHIOPHENES

Preparation of benzothiophenes with particular substituents on the benzene or thiophene moiety is described and their cycloaddition, oxidation, and reduction reactions are discussed.

Unexpected Diels-Alder and Oxidation Reactions of Benzothiophenes

The oxidation of thiophenes by peracids to form thiophene S-oxides could not be carried out with benzothiophenes.With the sterically hindered compound 1a the quinones 2 and 3 were produced whereas the anisyl-substituted derivative 1b formed the sulfine 5.Significantly different behavior of 1a and 1b was also observed for the Diels-Alder reaction with N-phenylmaleimide.The unexpected and unusual adduct 6 was the only product formed from 1a, with low yield though, whereas the normal Diels-Alder adduct was obtained from 1b.