6307-08-0

Basic information

• Product Name: N,N-diethylnaphthalene-2-sulfonamide
• Synonyms: 2-naphthalenesulfonamide, N,N-diethyl-; N,N-Diethylnaphthalene-2-sulfonamide
• CAS NO: 6307-08-0
• Molecular Formula: C₁₄H₁₇NO₂S
• Molecular Weight: 263.3553
• Mol File: 6307-08-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 411.5°C at 760 mmHg
• Flash Point: 202.6°C
• Density: 1.185g/cm³
• Vapor Pressure: 5.58E-07mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: N,N-diethylnaphthalene-2-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethylnaphthalene-2-sulfonamide(6307-08-0)
• EPA Substance Registry System: N,N-diethylnaphthalene-2-sulfonamide(6307-08-0)

Safety Data

• Hazardous Substances Data: 6307-08-0(Hazardous Substances Data)

Upstream product

• 109-89-7 diethylamine 
• 93-11-8 2-Naphthalenesulfonyl chloride 
• 63735-42-2 sodium naphthalen-2-ylsulfinate 
• 121-44-8 triethylamine 
• 150-77-6 N,N,N',N'-Tetraethylethylenediamine 
• 10151-46-9 2-naphthylsulfonyl hydrazide 
• 91-20-3 naphthalene 
• 20588-68-5 N,N-diethylsulfamoyl chloride 

Relevant articles and documents

NaI-Catalyzed Oxidative Amination of Aromatic Sodium Sulfinates: Synergetic Effect of Ethylene Dibromide and Air as Oxidants

A novel NaI-catalyzed oxidative amination of sodium sulfinates, employing both ethylene dibromide (EDB) and air as the oxidants, is described. EDB was first demonstrated to be a promising mild organic oxidant that in air, converted NaI into molecular iodine to promote the cross-coupling reactions of aromatic sodium sulfinates with amines to produce arylsulfonamides. Mechanistic studies indicated that a radical pathway might be involved in the reaction process.

METHOD OF INHIBITING APOLIPOPROTEIN-E EXPRESSION WHILE INCREASING EXPRESSION OF AT LEAST ONE OF LDL-RECEPTOR PROTEIN OR ABCA1 PROTEIN COMPRISING ADMINISTERING A SMALL COMPOUND

This invention offers an effective method of decreasing expression of apolipoprotein E and increasing expression of at least one of either LDL-receptor protein or AbcA1 protein including selecting mammalian cells expressing apoE and at least one of either LDL-receptor protein or AbcA1 protein, contacting the mammalian cell with an effective amount of a compound having general formula (I) or general formula (II) in an amount sufficient to decrease expression of the apoE and increase expression of at least one of the LDL-receptor protein or the AbcA1 protein in the mammalian cell.

Para-Selective Alkylation of Sulfonylarenes by Cooperative Nickel/Aluminum Catalysis

A method for the para-selective alkylation of a variety of arenesulfonamides and aromatic sulfones with 1-alkenes by cooperative nickel/aluminum catalysis has been developed. Taking advantage of the sulfornyl functionality serving as a removable ortho-directing group, the reaction can be applied to facile access to 1,3-dialkyl-substitued benzenes.