6310-23-2

Basic information

• Product Name: (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one
• Synonyms: (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one
• CAS NO: 6310-23-2
• Molecular Formula: C₁₃H₉ClOS
• Molecular Weight: 248.73
• Mol File: 6310-23-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 388.8°C at 760 mmHg
• Flash Point: 188.9°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 2.98E-06mmHg at 25°C
• Refractive Index: 1.657
• CAS DataBase Reference: (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one(6310-23-2)
• EPA Substance Registry System: (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one(6310-23-2)

Safety Data

• Hazardous Substances Data: 6310-23-2(Hazardous Substances Data)

Usage

General Description

(E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one is a chemical compound with the molecular formula C13H9ClOS. It is a yellow crystalline powder that is commonly used in the synthesis of pharmaceuticals and agrochemicals. (E)-1-(5-chlorothiophen-2-yl)-3-phenyl-prop-2-en-1-one has been found to possess anti-inflammatory and antifungal properties, making it a potential candidate for the development of new drugs to treat various medical conditions. Additionally, it is also used in the production of fragrances and flavors due to its aromatic properties. However, it is important to handle this chemical with caution as it may cause irritation to the skin, eyes, and respiratory system upon exposure.

InChI:InChI=1/C13H9ClOS/c14-13-9-8-12(16-13)11(15)7-6-10-4-2-1-3-5-10/h1-9H/b7-6+

Upstream product

• 6310-09-4 2-acetyl-5-chlorothiophene 
• 100-52-7 benzaldehyde 

Downstream Products

• 1641550-63-1 C₁₃H₁₁ClN₂S 
• 286956-41-0 (5-Chloro-thiophen-2-yl)-(1-methyl-4-phenyl-1H-pyrrol-3-yl)-methanone 
• 188782-72-1 1-(5-chloro-2-thienyl)-4,4-dicyano-3-phenylbutanone 
• 286956-26-1 (5-Chloro-thiophen-2-yl)-(4-phenyl-1H-pyrrol-3-yl)-methanone 

Relevant articles and documents

An efficient synthesis of thiophene conjugated benzothiazepines: In vitro screening for their antimicrobial activity

A series of novel thiophene conjugated benzothiazepines were synthesized by the reaction of chalcones with 2-aminobenzenethiol in citrus juice medium. The new compounds were characterized by spectroscopic studies. Results of in vitro antimicrobial evaluation of newly synthesized compounds 5a-j shows that the compounds 5a and 5c have excellent antimicrobial inhibition in the range of 12.5-25.0 μg/ mL against bacteria S. aureus, E. coli, P. aeruginosa and fungi A. niger, A. flavus organisms comparable to ciprofloxacin and nystatin and therefore these compounds might acts as lead molecules as antimicrobial agents.

SOCl2 catalyzed cyclization of chalcones: Synthesis and spectral studies of some bio-potent 1H pyrazoles

Some aryl-aryl 1H pyrazoles have been synthesised by cyclization of aryl chalcones and hydrazine hydrate in the presence of SOCl2. The yields of the pyrazoles are more than 85%. These pyrazoles are characterized by their physical con