63124-11-8

Usage

Uses

Used in Chemical Synthesis:
2-Oxo-1,2-dihydroquinoline-6-carbonitrile is used as a precursor or intermediate in the chemical synthesis process. Its structural relevance makes it a valuable component in the production of various compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Oxo-1,2-dihydroquinoline-6-carbonitrile is used as a building block for the synthesis of potential drug candidates. Its embedded functional groups facilitate the creation of new molecules with therapeutic properties.
Used in Research and Development:
2-Oxo-1,2-dihydroquinoline-6-carbonitrile is utilized in research and development settings to explore its chemical properties and potential applications. Scientists may investigate its reactivity, stability, and interactions with other molecules to uncover new uses and improve existing processes.

InChI:InChI=1/C10H6N2O/c11-6-7-1-3-9-8(5-7)2-4-10(13)12-9/h1-5H,(H,12,13)

Upstream product

• 1810-66-8 6-bromo-2-quinolone 
• 544-92-3 copper(I) cyanide 
• 327058-51-5 N-(4-bromophenyl)-(E)-3-ethoxyacrylamide 
• 23395-72-4 quinoline-6-carbonitrile 

Downstream Products

• 78060-54-5 2-chloroquinoline-6-carbonitrile 

Relevant academic research and scientific papers

2 - (1 H) - quinoline compound of microwave-assisted synthesis method (by machine translation)

The invention belongs to the field of organic intermediate synthesis, in particular discloses a 2 - (1 H) - quinoline compound of microwave-assisted synthetic method: quinoline raw material, and water in a reaction promoter and microwave under the assistance of the addition reaction, to obtain the 2 - (1 H) - quinoline compound; the quinoline raw material is quinoline, or on the quinoline ring in addition to the 2 other than the position of the substituent on the quinoline derivatives containing; the reaction accelerator is 2 - chloroethyl ester and/or 2 - [...] ester. The method raw materials are easy, simple reaction conditions, the reaction time is short, green energy-saving, reaction selectivity and high yield, excellent substrate functional group compatibility, and has high application value. (by machine translation)

UREA AND THIOUREA SUBSTITUTED BICYCLES DERIVATIVES AS PESTICIDES

The present invention relates to compounds of formula (I) a compound of formula (1') as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and

2-(4-Alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists

With the aim of identifying structurally novel, centrally acting histamine H3 antagonists, a series of 2-(4-alkylpiperazin-1-yl)quinolines was prepared. Systematic variation of the substituents led to highly potent histamine H3 antagonists with low polar surface area and appropriate log P for blood-brain barrier penetration.

Novel aryl- and heteroarylpiperazines

Novel aryl- and heteroarylpiperazines, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employing these compounds and compositions. The compounds show a high and selective binding affinity to the histamine H3 receptor indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity. As a result, the compounds are useful for the treatment of diseases and disorders related to the histamine H3 receptor.