6318-40-7Relevant articles and documents
Synthesis and Optical Properties of the New Acetylene Kaede Chromophore Analog
Baranov, M. S.,Mishin, A. S.,Smirnov, A. Yu.,Zaitseva, E. R.
, p. 458 - 461 (2020)
Abstract: A novel derivative of acetylene Kaede protein chromophore (Z)-2-((4-(diethylamino) phenyl) ethynyl)-5-(4-hydroxybenzylidene)-3-methyl-3,5-dihydro-4H-imidazol-4-one was synthesized by a modified Sonogashira reaction. In comparison with the classi
Evaluation of michael-type acceptor reactivity of 5-benzylidenebarbiturates, 5-benzylidenerhodanines, and related heterocycles using NMR
Arsovska, Emilija,Trontelj, Jurij,Zidar, Nace,Tomai, Tihomir,Mai, Lucija Peterlin,Kikelj, Danijel,Plavec, Janez,Zega, Anamarija
, p. 637 - 644 (2014/12/11)
Despite existing experimental and computational tools to assess the risk, the non-specific chemical modification of protein thiol groups remains a significant source of false-positive hits, particularly in academic drug discovery. Herein, we describe the
Benzylidene-linked thiohydantoin derivatives as inhibitors of tyrosinase and melanogenesis: Importance of the β-phenyl-α,β-unsaturated carbonyl functionality
Kim, Hye Rim,Lee, Hye Jin,Choi, Yeon Ja,Park, Yun Jung,Woo, Youngwoo,Kim, Seong Jin,Park, Min Hi,Lee, Hee Won,Chun, Pusoon,Chung, Hae Young,Moon, Hyung Ryong
, p. 1410 - 1417 (2014/10/15)
Based on the structural characteristics of the heterocyclic scaffolds of substituted benzylidene-hydantoin, -pyrrolidinedione, and -thiazolidinedione derivatives with potent tyrosinase inhibitory activity, substituted benzylidene derivatives with a 2-thio
