632352-74-0Relevant academic research and scientific papers
HETEROCYCLIC COMPOUND
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, (2019/09/05)
The present invention relates to N-((3S,4R)-1-((8-chloroquinoxalin-6-yl)carbonyl)-3-(4-fluorophenyl)piperidin-4-yl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide, which is a compound that can be useful for the treatment or prevention of SPT-related diseases including congenital diseases associated with the storage of sphingolipids, such as cancer and Niemann-Pick disease, or a salt thereof.
HETEROCYCLIC COMPOUND
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, (2018/03/25)
The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
FUSED TRIAZOLE TACHYKININ RECEPTOR ANTAGONISTS
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Page/Page column 19, (2008/06/13)
The present invention is directed to certain fused triazole compounds which are useful as neurokinin-1 (NK-I) receptor antagonists, and inhibitors of tachykinin and in particular substance P- The invention is also concerned with pharmaceutical formulation
CYCLOALKYL KETO PIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS
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Page/Page column 20, (2008/06/13)
The present invention is directed to certain piperidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations co
PIPERIDINYL PIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS
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Page/Page column 21, (2010/11/08)
The present invention is directed to certain piperidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations co
CYCLOALKYL PIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS
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Page/Page column 20, (2010/11/08)
The present invention is directed to certain piperidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations co
PIPERIDINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE
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Page/Page column 48, (2008/06/13)
The present invention provides a compound represented by the formula: ???wherein Ar is an aryl group, an aralkyl group or an aromatic heterocyclic group, each of which may be substituted, R1 is a hydrogen atom, an optionally substituted hydroca
