6324-75-0

Basic information

• Product Name: 2-methyl-6-(phenylmethylene)cyclohexan-1-one
• Synonyms: 2-methyl-6-(phenylmethylene)cyclohexan-1-one;2-Benzylidene-6-methylcyclohexanone;2-Methyl-6-(phenylmethylene)cyclohexanone;2-Methyl-6-benzylidenecyclohexanone;Einecs 228-687-4
• CAS NO: 6324-75-0
• Molecular Formula: C₁₄H₁₆O
• Molecular Weight: 200.27624
• EINECS: 228-687-4
• Mol File: 6324-75-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 335.7°C at 760 mmHg
• Flash Point: 142.1°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 0.000118mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 2-methyl-6-(phenylmethylene)cyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-6-(phenylmethylene)cyclohexan-1-one(6324-75-0)
• EPA Substance Registry System: 2-methyl-6-(phenylmethylene)cyclohexan-1-one(6324-75-0)

Safety Data

• Hazardous Substances Data: 6324-75-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H16O/c1-11-6-5-9-13(14(11)15)10-12-7-3-2-4-8-12/h2-4,7-8,10-11H,5-6,9H2,1H3/b13-10-

Upstream product

• 100-52-7 benzaldehyde 
• 5292-69-3 6-methyl-1-(4-morpholinyl)cyclohexene 
• 3008-43-3 3-methylcyclohexane-1,2-dione 
• 67-56-1 methanol 
• 5682-83-7 2-Benzylidenecyclohexanone 
• 19980-33-7 6-methyl-1-trimethylsiloxycyclohex-1-ene 
• 583-60-8 2-Methylcyclohexanone 
• 141-52-6 sodium ethanolate 

Downstream Products

• 102690-97-1 4-hydroxy-3-<α-(3-methyl-2-oxocyclohexyl)benzyl>coumarin 
• 1192269-63-8 1-methyl-5-phenyl-1,2,3,4-tetrahydrobenzo[a]phenanthridine 
• 72947-08-1 9a-Benzyl-6b-methyl-7,8,9,9a-tetrahydro-6bH-pentaleno[2,1-a]naphthalen-10-one 
• 72947-04-7 8a-Benzyl-3a-methyl-2,3,3a,8a-tetrahydro-1H-cyclopenta[a]inden-8-one 
• 31089-34-6 6-Benzyl-2-methyl-cyclohex-2-en-1-on 
• 1208-44-2 2-benzyl-6-methyl-cyclohex-2-enone 
• 24785-76-0 2-benzyl-6-methylcyclohexan-1-one 
• 1427056-00-5 C₂₀H₂₁N₃O₂S 

Relevant articles and documents

RhIII-Catalyzed Synthesis of Highly Substituted 2-Pyridones using Fluorinated Diazomalonate

A RhIII-catalyzed strategy was developed for the rapid construction of highly substituted 2-pyridone scaffolds using α,β-unsaturated oximes and fluorinated diazomalonate. The reaction proceeds through direct, site-selective alkylation based on migratory insertion and subsequent cyclocondensation. A wide substrate scope with different functional groups was explored. The requirement of fluorinated diazomalonate was explored for this transformation. The developed methodology was further extended with the synthesis of the bioactive compound.

Manganese catalyzed α-methylation of ketones with methanol as a C1 source

The direct α-methylation of ketones with methanol under hydrogen borrowing conditions using a well-defined manganese PN3P complex as a pre-catalyst was, for the first time, achieved. The reactions typically proceed at 120 °C for 20 h with 3 mol% pre-catalyst loading and in the presence of NaOtBu (50 mol%) as base. The scope of the reaction was extended to the α-methylation of esters.

Platinum-catalyzed cyclization/[1,2]-alkyl migration/allyl shift/cyclization cascade of epoxy alkynyl allyl ethers: A step-economical route to spirobenzo[h]chromanones

In tandem: A PtI4-catalyzed tandem reaction of epoxy alkynyl allyl ethers involving a cyclization, [1,2]-alkyl migration, O→C allyl shift, aromatic cyclization sequence has been achieved to synthesize spirobenzo[h]chromanones. The reaction simultaneously forms two adjacent stereocenters, one of which is a quaternary carbon atom (see scheme). Copyright