63253-20-3

Upstream product

• 75-87-6 chloral 
• 100-66-3 methoxybenzene 
• 75-36-5 acetyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 14337-31-6 2,2,2-trichloro-1-(4-methoxyphenyl)ethan-1-ol 
• 108-24-7 acetic anhydride 
• 38561-12-5 1-(p-methoxyphenyl)-2,2,2-trichloroethyl p-toluenesulphonate 

Downstream Products

• 934372-09-5 (Z)-2-chloro-5-benzyloxy-1-(4-methoxyphenyl)pent-1-ene 
• 934372-10-8 (Z)-2-chloro-(4-methoxyphenyl)non-1-ene 
• 934372-04-0 (Z)-2-chloro-1-(4-methoxyphenyl)-5-phenylpent-1-ene 
• 41448-64-0 1-(2,2-dichlorovinyl)-4-methoxybenzene 

Relevant academic research and scientific papers

Suzuki-Miyaura cross-coupling of 1,1-dichloro-1-alkenes with 9-alkyl-9-BBN

We addressed an unexplored application of the Suzuki-Miyaura protocol to the cross-coupling of 1,1-dichloro-1-alkenes with 9-alkyl-9-BBN. The use of bisphosphine ligands with a large P-Pd-P bite angle allowed us to synthesize Z-chlorinated internal alkenes in good yields resulting from a selective monocoupling process, a recurrent challenge with 1,1-dichloro-1-alkenes. Moreover, these monochlorinated olefins could be further transformed providing stereospecifically trisubstituted olefins.

Solvolysis of 1-Aryl-2,2,2-trihalogenoethyl Toluene-p-sulphonates. Generation of Carbocations Destabilized by Trichloro- or Tribromo-methyl Groups

The kinetics of solvolysis of the title compounds, leading to the formation of carbocations destabilized by a CCl3 or a CBr3 group, have been studied in various solvents.Destabilization by the CX3 group increases with the electronegativity of the halogen