6333-07-9

Basic information

• Product Name: 2'-Hydroxy-1'-benzonaphthone
• Synonyms: (2-Hydroxy-1-naphtyl)phenyl ketone;1-Benzoyl-2-naphthol;2'-Hydroxy-1'-benzonaphthone;2-Hydroxy-1-naphtylphenylmethanone;Phenyl(2-hydroxy-1-naphtyl) ketone
• CAS NO: 6333-07-9
• Molecular Formula: C₁₇H₁₂O₂
• Molecular Weight: 248.276
• Mol File: 6333-07-9.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 411°Cat760mmHg
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 2.42E-07mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: 2'-Hydroxy-1'-benzonaphthone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Hydroxy-1'-benzonaphthone(6333-07-9)
• EPA Substance Registry System: 2'-Hydroxy-1'-benzonaphthone(6333-07-9)

Safety Data

• Hazardous Substances Data: 6333-07-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H12O2/c18-15-11-10-12-6-4-5-9-14(12)16(15)17(19)13-7-2-1-3-8-13/h1-11,18H

Upstream product

• 98-88-4 benzoyl chloride 
• 135-19-3 β-naphthol 
• 100-47-0 benzonitrile 
• 93-04-9 2-Methoxynaphthalene 
• 93-99-2 benzoic acid phenyl ester 
• 98-07-7 Benzotrichlorid 
• 618-32-6 Benzoyl bromide 
• 4903-36-0 N-phenyl-benzimidoyl chloride 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 98-80-6 phenylboronic acid 
• 374690-61-6 1-(phenyl(pirrolidine-1-yl)methyl)naphthalen-2-ol 
• 93-97-0 benzoic acid anhydride 
• 872799-22-9 (2-hydroxy-[1]naphthyl)-phenyl ketone-imine 
• 15431-97-7 1-(N-Phenylbenzimidoyl)-2-naphthol 

Downstream Products

• 30982-59-3 1,2-diphenyl-benzo[f]chromen-3-one 
• 125796-54-5 3-benzyl-4-phenyl-5,6-benzocoumarin 
• 117139-07-8 2-Chloro-1-phenyl-benzo[f]chromen-3-one 
• 74424-80-9 <1-(2-hydroxynaphthyl)>diphenylmethanol 
• 154423-48-0 (4-benzyloxyphenyl)-(2-hydroxynaphth-1-yl)-phenyl-methanol 
• 154423-56-0 1-{Hydroxy-phenyl-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-methyl}-naphthalen-2-ol 
• 94866-93-0 <1-Benzoyl-naphthyl-(2)-oxy>-essigsaeure-aethylester 
• 1446242-95-0 3-oxo-1-phenyl-3H-benzo[f]chromene-2-carbonitrile 
• 374690-61-6 1-(phenyl(pirrolidine-1-yl)methyl)naphthalen-2-ol 

Relevant articles and documents

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Cu/Ag mediated peroxide-free synthesis of benzoylated naphthol derivatives

A peroxide-free methodology was developed for the synthesis of benzoylated naphthol/phenol derivatives through oxidative deamination reaction performed under aerobic reaction conditions. A synergistic combination of Cu(OTf)2 and Ag2O was used to convert the aminonaphthols and aminophenols to the corresponding benzoylated derivatives. The definite role of atmospheric oxygen to assist the reaction was proved by performing the reaction in the argon atmosphere.

Efficient microwave-assisted direct C-benzoylation of phenols and naphthols with benzoic acid catalyzed by bismuth triflate under solvent-free or ionic liquid conditions

An efficient and simple route for the synthesis of ortho-hydroxyaryl ketones has been developed. The microwave-assisted direct C-benzoylation of phenols and naphthols in the presence of metal triflates afforded the corresponding ortho-hydroxyaryl ketones in moderate to excellent yields. Bismuth triflate showed the best catalytic performance compared to other metal triflates. The protocol has advantages including short reaction times, high chemoselectivity towards C-acylation, and simple work-up. Additionally, bismuth triflate can be easily recovered and reused several times without significant loss of catalytic performance.