Catalytic High Pressure Synthesis of Hindered β-Aminoesters

Article abstract of DOI:10.1016/0040-4039(94)02215-W

Hindered β-aminoesters are obtained in fair to high yields by the conjugate addition of amines to α,β-unsaturated esters, both substrates harbouring bulky groups, under high pressure in the presence of catalytic amounts of ytterbium triflate.