6337-25-3

Basic information

• Product Name: (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine
• Synonyms: (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine
• CAS NO: 6337-25-3
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.25852
• Mol File: 6337-25-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 135 °C
• Boiling Point: 364°C at 760 mmHg
• Flash Point: 174°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 6.15E-06mmHg at 25°C
• Refractive Index: 1.556
• PKA: 11.40±0.70(Predicted)
• CAS DataBase Reference: (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine(6337-25-3)
• EPA Substance Registry System: (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine(6337-25-3)

Safety Data

• Hazardous Substances Data: 6337-25-3(Hazardous Substances Data)

Usage

General Description

(NZ)-N-[1-(4-phenoxyphenyl)ethylidene] hydroxylamine is a chemical compound with the molecular formula C14H14NO2. It is a derivative of hydroxylamine and has a phenoxyphenyl group attached to the ethylidene carbon. (NZ)-N-[1-(4-phenoxyphenyl)ethylidene]hydroxylamine is commonly used in organic synthesis as a reagent for the preparation of various organic compounds. It is also used as a pharmaceutical intermediate and in the production of some dyes. Additionally, it has potential applications in the field of medicinal chemistry due to its unique structure and reactivity. Overall, (NZ)-N-[1-(4-phenoxyphenyl)ethylidene] hydroxylamine is a versatile compound with a range of industrial and research applications.

InChI:InChI=1/C14H13NO2/c1-11(15-16)12-7-9-14(10-8-12)17-13-5-3-2-4-6-13/h2-10,16H,1H3/b15-11+

Upstream product

• 108-90-7 chlorobenzene 
• 101-84-8 diphenylether 
• 5031-78-7 4-phenoxyacetophenone 

Downstream Products

• 6312-87-4 p-phenoxyacetanilide 
• 139-59-3 4-phenoxyanilin 
• 315248-48-7 N-acetyl-sulfanilic acid-(4-phenoxy-anilide) 
• 115513-99-0 N-Hydroxy-N-[1-(4-phenoxy-phenyl)-ethyl]-acetamide 
• 100-19-6 (4-nitrophenyl)ethanone 
• 10342-64-0 p-nitroacetophenone oxime 
• 5031-78-7 4-phenoxyacetophenone 
• 102077-19-0 1-(4-phenoxyphenyl)ethylamine 

Relevant articles and documents

Design, synthesis, herbicidal activity, and the molecular docking study of novel diphenyl ether derivatives as protoporphyrinogen IX oxidase inhibitors

Protoporphyrinogen oxidase (PPO, EC 1.3.3.4) is an important herbicide target. In this study, a series of novel diphenyl ethers derivatives with 2-pyrrolidone structure were developed as PPO inhibitors. Thereinto, compound H7 (IC50 = 0.0262 mg/L) has better PPO enzyme inhibitory activity than commercial herbicide oxyfluorfen (IC50 = 0.0426 mg/L). Greenhouse herbicidal activity experiments exhibited that even under the condition of 37.5 g ai/ha, H7 still had excellent broad-spectrum herbicidal activity. Moreover, rice, peanut, and cotton had strong tolerance to H7 at 300 g ai/ha. Field trial showed that H7 had comparable herbicidal activity to oxyfluorfen. These experimental results indicated that H7 could be developed as a novel PPO Inhibitor candidate for weed control in the field.

Facile preparation of 5-alkyl-1-aryltetrazoles with arenes, acyl chlorides, hydroxylamine, and diphenylphosphoryl azide

Successive treatment of arenes with acyl chlorides and AlCl3, the addition of water and removal of solvent, the reaction with NH2OH?HCl and K2CO3, and the reaction with diphenylphosphoryl azide and DBU under warming conditions gave the corresponding 5-alkyl-1-aryltetrazoles efficiently in good to moderate yields. The present method is one-pot transformation of arenes into 5-alkyl-1-aryltetrazoles using the Friedel-Crafts acylation and the Beckmann rearrangement under transition-metal-free conditions.