6338-98-3 Usage
Uses
Used in Pharmaceutical Industry:
7-Chloro-8-aminoquinoline is used as a starting material for the production of antimalarial drugs, such as primaquine and tafenoquine. It plays a crucial role in the synthesis of these medications, which are effective in treating and preventing malaria.
Used in Chemical Research:
7-Chloro-8-aminoquinoline is also utilized in chemical research as a building block for the synthesis of various other compounds, including potential pharmaceuticals and chemical intermediates. Its unique structure allows for further modification and exploration of its properties and potential applications in different fields.
Check Digit Verification of cas no
The CAS Registry Mumber 6338-98-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6338-98:
(6*6)+(5*3)+(4*3)+(3*8)+(2*9)+(1*8)=113
113 % 10 = 3
So 6338-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2/c10-7-4-3-6-2-1-5-12-9(6)8(7)11/h1-5H,11H2
6338-98-3Relevant academic research and scientific papers
Industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles-catalyzed hydrogenation of nitroarenes
Fu, Lihua,Li, Dingzhong,Lu, Hao,Qiu, Renhua,Sun, Tulai,Xing, Chen,Yang, Tianbao
, (2022/01/11)
The development of green and efficient methods for hydrogenation of nitroarenes is still highly demanding in organic synthesis. Herein, we report an industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles process for the synthesis of aryl amines with good yields via hydrogenation of nitroarenes. Nine key anti-cancer drug intermediates were successfully achieved with protocol. And Osimertinib intermediate 4m can be smoothly synthesized at a 2.67 kg-scale with >99.5% HPLC purity. This protocol features cheap carbon source, highly catalytic activity, simple operation, kilogram-scalable and recyclable catalysts (eight times without observable losing activity).
