6338-98-3 Usage
General Description
7-Chloro-8-aminoquinoline is a chemical compound that falls under the category of aminoquinolines. It is commonly used as a starting material in the production of antimalarial drugs, including primaquine and tafenoquine. Its chemical formula is C15H11ClN2, and it appears as a white to off-white solid powder. Its molecular weight is 256.71 g/mol. However, its handling requires specific precautions as it may cause skin and eye irritation or other health risks, hence protective equipment is recommended during its use.
Check Digit Verification of cas no
The CAS Registry Mumber 6338-98-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6338-98:
(6*6)+(5*3)+(4*3)+(3*8)+(2*9)+(1*8)=113
113 % 10 = 3
So 6338-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2/c10-7-4-3-6-2-1-5-12-9(6)8(7)11/h1-5H,11H2
6338-98-3Relevant articles and documents
Industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles-catalyzed hydrogenation of nitroarenes
Fu, Lihua,Li, Dingzhong,Lu, Hao,Qiu, Renhua,Sun, Tulai,Xing, Chen,Yang, Tianbao
, (2022/01/11)
The development of green and efficient methods for hydrogenation of nitroarenes is still highly demanding in organic synthesis. Herein, we report an industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles process for the synthesis of aryl amines with good yields via hydrogenation of nitroarenes. Nine key anti-cancer drug intermediates were successfully achieved with protocol. And Osimertinib intermediate 4m can be smoothly synthesized at a 2.67 kg-scale with >99.5% HPLC purity. This protocol features cheap carbon source, highly catalytic activity, simple operation, kilogram-scalable and recyclable catalysts (eight times without observable losing activity).
