63416-82-0

Upstream product

• 917-64-6 methyl magnesium iodide 
• 63416-61-5 4-(4-fluorophenyl)-2-butanone 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 75-65-0 tert-butyl alcohol 
• 136265-10-6 ethyl 4-fluorocinnamate 
• 75-16-1 methylmagnesium bromide 
• 88023-07-8 ethyl 2-<(4-fluorophenyl)methyl>-3-oxobutanoate 

Downstream Products

• 63416-81-9 3-(4-fluorophenyl)-1,1-dimethylpropanamine hydrochloride 
• 143627-92-3 1-Benzoyl-3-[3-(4-fluoro-phenyl)-1,1-dimethyl-propyl]-thiourea 
• 143627-93-4 N-<3-(4-fluorophenyl)-1,1-dimethylpropyl>thiourea 
• 63416-84-2 3-(4-fluorophenyl)-1,1-dimethylpropanamine 
• 143627-96-7 N-[3-(4-Fluoro-phenyl)-1,1-dimethyl-propyl]-formamide 

Relevant academic research and scientific papers

Controllable Intramolecular Unactivated C(sp3)-H Amination and Oxygenation of Carbamates

Dual catalyst-controlled intramolecular unactivated C(sp3)-H amination and oxygenation of carbamates merging visible-light photocatalysis and earth-abundant transition metal catalysis have been reported. Useful amino alcohol and diol derivatives could be selectively obtained from readily available tertiary alcohol derivatives. The possible mechanisms have been proposed via a 1,5-HAT process followed by Lewis acid-controlled cyclization. The nickel and zinc catalysts inhibit the formation of oxygenation and amination products, respectively. An interesting phenomenon of chirality transfer is also observed.

Synthesis and histamine H2-agonistic activity of ring-substituted phenyl analogues of impromidine

Analogues of the H2-agonist impromidine, characterized by a substituted phenyl ring instead of the 5-methyl-4-imidazolyl group, were prepared and tested for their H2-agonistic and H1-antagonistic activity at the guinea-pig

Photochemical Transformations. 26. Sensitized and Unsensitized Photoreactions of Some Benzyl Chlorides in tert-Butyl Alcohol

Benzyl chloride and a variety of meta- and para-substituted derivatives have been irradiated in tert-butylalcohol at 254 nm or in acetone-tert-butyl alcohol mixtures at 300 nm.Quantum and chemical yields of photosolvolysis products (benzyl tert-butyl ether and/or benzyl alcohol), photohomolysis products (bibenzyl and 4-phenyl-2-methyl-2-butanol), and corresponding products from substituted benzylchlorides have been measured as functions of substrate concentration and medium composition.Sensitized reactions favor bond heterolysis, but direct irradiations favor homolysis, although reactions are not clean in either case.There is no correlation between quantum yields for photosolvolysis and Hammett ? or Brown ?+ constants, and no salt effects of added lithium perchlorate were observed, in either direct or sensitized reactions.

4-Hydroxy-1,3-benzenedimethanol derivatives

Compounds of the general formula (I): STR1 in which one or more substituents R1 may be present and in which: R1 represents a halogen atom, preferably fluorine or chlorine, or a trifluoromethyl group or a group --NR5 R6 in which R5 and R6 which may be the same or different represent a hydrogen atom, or an alkyl group containing from 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms or an acyl group, preferably the residue of a C1 -C6 alkanoic acid; X represents a straight or branched chain alkyl group containing 2 to 6 carbon atoms; and R2 and R3 which may be the same or different each represent a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, preferably a methyl group; and R4 represents a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, are provided together with processes for the production thereof. They have a β2 -stimulant activity.