6342-46-7

Basic information

• Product Name: N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE
• Synonyms: ZERENEX E/6026546;N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE;ISONICOTINIC ACID (4-CHLORO-BENZYLIDENE)-HYDRAZIDE;4-PYRIDINECARBOXYLIC ACID N-(4-CHLOROBENZYLIDENE)HYDRAZIDE
• CAS NO: 6342-46-7
• Molecular Formula: C₁₃H₁₀ClN₃O
• Molecular Weight: 259.69
• Mol File: 6342-46-7.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE(6342-46-7)
• EPA Substance Registry System: N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE(6342-46-7)

Safety Data

• Hazardous Substances Data: 6342-46-7(Hazardous Substances Data)

Usage

General Description

N'-(4-chlorobenzylidene)isonicotinohydrazide is a chemical compound with the molecular formula C13H10ClN3O. It is a hydrazide derivative used in organic synthesis and pharmaceutical research. N'-(4-CHLOROBENZYLIDENE)ISONICOTINOHYDRAZIDE exhibits potential anti-inflammatory and antitumor properties, and it has been studied for its potential as a drug candidate for the treatment of various diseases. Additionally, N'-(4-chlorobenzylidene)isonicotinohydrazide has been investigated for its antimicrobial activity and as a potential agent for the development of new drugs to combat antibiotic resistance. Furthermore, it has shown promise for its ability to inhibit the growth of certain cancer cells and may have applications in cancer therapy.

Upstream product

• 54-85-3 isoniazid 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 79844-21-6 N-[2-(4-chlorophenyl)-4-oxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide 
• 1152134-78-5 N-[3-chloro-2-(4-chlorophenyl)-4-oxoazetidin-1-yl]isonicotinamide 
• 382178-47-4 2-(4-chlorophenyl)-3-acetyl-5-(pyridin-4-yl)-2,3-dihydro-1,3,4-oxadiazole 
• 586-95-8 pyridine-4-methanol 
• 104-86-9 4-chlorobenzylamine 

Relevant articles and documents

Synthesis, characterization, in silico studies and in vitro biological evaluation of isoniazid-hydrazone complexes

Isoniazid-hydrazone complexes (IHCs) were synthesized and thoroughly characterized by FT-IR, 1H NMR and 13C NMR spectroscopic techniques. The anti-inflammatory and antidiabetic activities were tested for the IHCs using protein denatu

Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies

Change in life style and eating habits has led to an increased prevalence of hyperuricemia worldwide. The role of hyperuricemia is no more restricted to gout, but it has a central role in progression of CVD, hypertension, metabolic syndrome, and arthritis

Eco-friendly and highly efficient synthesis, including multigram synthesis, of aldehyde isonicotinoyl hydrazones using sonochemistry

Background: The isoniazid has been a key compound in first-line tuberculosis (TB) treatment, usually in combination with other drugs. Following on from the use of isoniazid itself, various derivatives of isoniazid have also been investigated as anti-TB ag