63438-53-9 Usage
General Description
(S)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide, also known as piracetam, is a nootropic drug that is commonly used to enhance cognitive function and improve memory. It is a derivative of the neurotransmitter GABA and is believed to work by modulating neurotransmission. Piracetam has also been studied for its potential neuroprotective and neurotrophic effects, making it a potential candidate for treating neurodegenerative disorders. Additionally, piracetam has been shown to improve learning and memory in animal models and has been used in the treatment of cognitive impairment and dementia. While its exact mechanism of action is not fully understood, piracetam is generally considered to be relatively safe and well-tolerated, with few reported side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 63438-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,4,3 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 63438-53:
(7*6)+(6*3)+(5*4)+(4*3)+(3*8)+(2*5)+(1*3)=129
129 % 10 = 9
So 63438-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H12N2O2/c1-9(2)7(11)5-3-4-6(10)8-5/h5H,3-4H2,1-2H3,(H,8,10)
63438-53-9Relevant articles and documents
Synthesis and bioactivities evaluation of L-pyroglutamic acid analogues from natural product lead
Gang, Fang-li,Zhu, Feng,Li, Xiao-ting,Wei, Jie-lu,Wu, Wen-jun,Zhang, Ji-wen
, p. 4644 - 4649 (2018/08/21)
A series of L-pyroglutamic acid analogues from natural product lead were designed and synthesized, as well as their antifungal activities against Phytophthora infestans, neuritogenic activities, antibacterial activities and anti-inflammatory activities are described. The bioassays and SAR study showed that the majority of L-pyroglutamic acid esters have a significant antifungal activity against P. infestans, especially 2d and 2j demonstrated the best activities with EC50 values of 1.44 and 1.21 μg mL?1, which were about seven times that of commercial azoxystrobin (7.85 μg mL?1). Moreover, compounds 2e, 2g and 4d displayed anti-inflammatory activity against LPS-induced NO production in BV-2 microglial cells; neuritogenic activity in NGF-induced PC-12 cells is the same activity. This study demonstrates that compounds 2d and 2j are potential drugs to control P. infestans.
