63459-07-4Relevant articles and documents
Electro-Mechanochemical Atom Transfer Radical Cyclizations using Piezoelectric BaTiO3
Bolm, Carsten,Hernández, José G.,Schumacher, Christian
, p. 16357 - 16360 (2020)
The formation and regeneration of active CuI species is a fundamental mechanistic step in copper-catalyzed atom transfer radical cyclizations (ATRC). Typically, the presence of the catalytically active CuI species in the reaction mix
Asymmetric synthesis of Sedum alkaloids via lithium amide conjugate addition
Davies, Stephen G.,Fletcher, Ai M.,Roberts, Paul M.,Smith, Andrew D.
supporting information; experimental part, p. 10192 - 10213 (2010/02/28)
Conjugate addition of lithium (R)-N-allyl-N-(α-methylbenzyl)amide or lithium (R)-N-but-3-enyl-N-(α-methylbenzyl)amide to an alkyl hexa-2,4-dienoate or alkyl hepta-2,6-dienoate, followed by ring-closing metathesis of the olefin functionalities within the resultant β-amino ester, generates a range of diastereoisomerically pure azacycles in good yield. These homochiral templates are readily transformed to a range of piperidine alkaloids of the Sedum family, and the corresponding five-, seven- and eight-membered ring homologues.
