63471-87-4

Basic information

• Product Name: 4-(4-methoxybiphenyl-3-yl)-4-oxobutanoic acid
• CAS NO: 63471-87-4
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.3065
• Mol File: 63471-87-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 517.6°C at 760 mmHg
• Flash Point: 193°C
• Density: 1.195g/cm³
• Vapor Pressure: 1.54E-11mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: 4-(4-methoxybiphenyl-3-yl)-4-oxobutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxybiphenyl-3-yl)-4-oxobutanoic acid(63471-87-4)
• EPA Substance Registry System: 4-(4-methoxybiphenyl-3-yl)-4-oxobutanoic acid(63471-87-4)

Safety Data

• Hazardous Substances Data: 63471-87-4(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 7446-70-0 aluminium trichloride 
• 613-37-6 4-methoxylbiphenyl 
• 98-95-3 nitrobenzene 

Downstream Products

• 323-87-5 4-hydroxybiphenyl-3-carboxylic acid 
• 114508-47-3 5-(4-methoxy-biphenyl-3-yl)-5-(2-methoxy-phenyl)-dihydro-furan-2-one 
• 107410-07-1 2-methoxy-5-phenylbenzoic acid 

Relevant articles and documents

Fenbufen, a new anti inflammatory analgesic: synthesis and structure activity relationships of analogs

100 analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti inflammatory tests and the 2 phenyl 1,4 benzoquinone writhing and inflamed paw pressure analgesic tests. Only 3 retained the same full spectrum of activity as fenbufen: dl 4 (4 biphenylyl) 4 hydroxybutyric acid, dl 4 (4 biphenylyl) 1,4 butanediol, and 4 biphenylacetic acid. Fenbufen had the same spectrum of activity as aspirin, phenylbutazone, and indomethacin in the 5 tests. In addition, dose response derived potencies show fenbufen more potent than aspirin and at least as potent as phenylbutazone in all 5 tests. Two related compounds were generally similar.