63473-86-9

Upstream product

• 64-17-5 ethanol 
• 72277-01-1 diethyl 1-trimethylsilyloxy-3-phenyl-2-propenylphosphonate 
• 106-95-6 allyl bromide 
• 52129-49-4 3-phenylhex-5-enoic acid 
• 62114-59-4 diethyl malonyl-1 phenyl-1 butene-3 
• 21500-57-2 lithium dilallyl cuprate 
• 4192-77-2 ethyl cinnamate 
• 4028-23-3 Allylchlorodimethylsilane 
• 5764-85-2 Ethyl 3-hydroxy-3-phenylpropanoate 
• 14371-10-9 (E)-3-phenylpropenal 
• 5292-53-5 diethyl benzalmalonate 
• 100-52-7 benzaldehyde 

Downstream Products

• 122019-83-4 5,6-Dibromo-3-phenyl-hexanoic acid ethyl ester 
• 65559-66-2 N-methyl-3-phenyl-5-hexenamide 
• 62114-70-9 chloromethyl-2 methyl-1 phenyl-4 piperidine 
• 62114-62-9 N-methyl phenyl-3 hexene-5 yl amine 
• 65559-67-3 N-chloro N-methyl phenyl-3 hexene-5 yl amine 
• 62114-64-1 N,N-dimethyl phenyl-3 hexene-5 yl amine 
• 62114-65-2 N-allyl N-methyl phenyl-3 hexene-5 yl amine 
• 62114-71-0 methoxymethyl-2 methyl-1 phenyl-4 piperidine 
• 62114-66-3 N-benzyl N-methyl phenyl-3 hexene-5 yl amine 
• 80534-97-0 methyl-1 piperidinomethyl-2 phenyl-4 piperidine 
• 80534-95-8 N-methyl phenyl-3 hexene-5 yl trifluoroacetamide 
• 80534-96-9 N-methyl epoxy-5,6 phenyl-3 hexyl trifluoroacetamide 
• 80534-94-7 hydroxymethyl-2 methyl-1 phenyl-4 piperidine 
• 80534-94-7 hydroxymethyl-2 methyl-1 phenyl-4 piperidine 

Relevant academic research and scientific papers

Direct substitution of the hydroxy group in alcohols with silyl nucleophiles catalyzed by indium trichloride

Straightforward substitution: An excellent combination of a silyl nucleophile and indium catalyst was used to accomplish the dehydroxylation/ alkylation of alcohols under nearly neutral conditions (see scheme, Si = silyl group) even though this type of reaction usually requires at least an equimolar amount of acid.

Resolution and Determination of the Absolute Stereochemistry of α- and β-Aryl-Substituted γ-Methylenevalerolactones, Alternate Substrate Inhibitors for Serine Proteases

To study the enantioselectivity of alternate substrate inhibition of chymotrypsin by chiral α- and β-arylsubstituted enol lactones, we have prepared four of these lactones in homochiral form: 3-phenyl-6-methylenetetrahydro-2-pyranone (αPh6H, IIa), 3-(1-na

Silyl Phosphites. XVIII. Versatile Utility of α-(Trimethylsilyloxy)-alkylphosphonates as Key Intermediates for Transformation of Aldehydes into Several Carbonyl Derivatives

Carbonyl addition compounds of diethyl trimethylsilyl phosphite (DTMSP) with aldehydes were converted, by treatment with lithium diisopropylamide (LDA) followed by the successive alkylation and alkaline hydrolysis, to carbonyl derivatives involving aldehydes, unsymmetrical ketones, β,γ-unsaturated ketones, and carboxylic acids. β-Substituted carboxylic esters and γ-substituted lactones were prepared by use of the carbonyl addition compounds of DTMSP with α,β-unsaturated aldehydes.

SYNTHESE RADICALAIRE D'ANALGESIQUES POTENTIELS: ARYL-4 PIPERIDINES SUBSTITUEES EN 2 ET BENZOMORPHANES

The synthesis of a series of 3-aryl 5-hexenyl amines and the cyclisations of the corresponding N-chloroamines are described.When the ring closure results from the amino radical addition to the ethylenic double bond, 2-chloromethyl 4-phenyl piperidines are obtained.These compounds lead by intramolecular Friedel-Crafts reaction to varied substituted 6,7-benzomorphanes.When the phenyl ring is substituted with a methoxyl group, the cyclisation proceeds via homolytic aromatic substitution and 4-allyl tetrahydroquinolines are formed.

Facile synthesis of β-alkyl-substituted esters from α,β-unsaturated aldehydes

β-Alkyl-substituted carboxylates were synthesized in good yields from α,β-unsaturated aldehydes by using the 1:1 carbonyl adducts with diethyl bis (trimethylsilyl) phosphite.