63487-20-7Relevant academic research and scientific papers
A Four-Component Reaction for the Synthesis of β-Quinoline Allylic Sulfones under Iron Catalysis
Xiao, Fuhong,Liu, Chao,Yuan, Shanshan,Huang, Huawen,Deng, Guo-Jun
, p. 10420 - 10429 (2018)
An efficient strategy for the preparation of allylic sulfones has been developed. In this protocol, readily available 2-methylquinolines or 2-methylbenzothiazoles, sodium sulfinates, and dimethylacetamide (DMA) were successfully assembled under user-friendly iron catalysis, and DMA provided two carbons as a dual synthon. A broad range of functionalized heterocyclic allylic sulfones were accessed with a wide functional group tolerance.
