63547-61-5

Upstream product

• 1072-82-8 3-acetylpyrrole 
• 75-36-5 acetyl chloride 
• 1072-83-9 2-Acetylpyrrole 
• 109-97-7 pyrrole 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 147089-36-9 4-(2-Methyl-benzo[1,3]dithiol-2-yl)-2-(2-methyl-benzo[1,3]oxathiol-2-yl)-1H-pyrrole 
• 81453-98-7 3-acetyl-1-(phenylsulfonyl)pyrrole 
• 147089-57-4 2,4-Bis-(2-methyl-benzo[1,3]dithiol-2-yl)-1H-pyrrole 
• 147089-10-9 1-[5-(2-Methyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-3-yl]-ethanone 
• 147089-46-1 1-[4-(2-Methyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-2-yl]-ethanone 
• 129666-99-5 2-acetyl-1-(4-toluenesulfonyl)pyrrole 

Downstream Products

• 850913-19-8 1-[5-acetyl-1-(toluene-4-sulfonyl)-1H-pyrrol-3-yl]-ethan-1-one 

Relevant academic research and scientific papers

Zinc mediated straightforward access to diacylpyrroles

In this article, we report the preparation of various 2,4- and 2,5-diacylpyrroles via two zinc-mediated acylation reactions of non-protected pyrroles.

Amberlyst-15 catalyzed acetylation of heteroaromatics with acetic anhydride under solvent free conditions

Amberlyst-15 has been found to be an efficient reusable heterogeneous catalyst for acetylation of indole, 2-methylindole and pyrrole with acetic anhydride under solvent free conditions.

Synthesis and properties of polyquinolines and polyanthrazolines containing pyrrole units in the main chain

A series of eight new polyquinolines and polyanthrazolines with pyrrole isomeric units in main chain were synthesized and characterized. The new polymers showed high glass transition temperatures (Tg = 242-339°C) and excellent thermal stability (T5% = 398-536°C in air, TGA). Compared to the series of polyanthrazolines, the series of polyquinolines exhibited higher thermal stability, better solubility in common organic solvents, and lower maximum absorption wavelengths (λmaxa). Polyanthrazolines with 2,5-pyrrole linkage showed an unusually high λmaxa (565 nm) and small band gap (2.02 eV). All polymers in solution had low photoluminescence quantum yields between 10-2% and 10-5% and excited-state lifetimes of 0.28-1.29 ns. The effects of molecular structure, especially pyrrole linkage structures, on the electronic structure, thermodynamics, and some of the optical properties of the polymers were explored. A model of hydrogen bonds in the main chain of the polymers was suggested to explain the difference in the properties of the isomer polymers. In addition, a polyquinoline (PBM) was chosen to examine the proton conductivity; the result indicated that the PBM/H3PO4 complex exhibited a high conductivity of 1.5 × 10-3 S cm-1 at 157°C. The new polymers are expected to have improved proton-conducting properties for the application as the membranes in fuel cells.

General Methods for Synthesizing 2,4-Diacylpyrroles and their Precursors Containing One or Two Masked Acyl Groups

A thorough study of the synthesis of 2,4-diacylpyrroles by direct acylation of pyrrole and 2- and 3-acylpyrroles is reported.Among these, Friedel-Crafts acylation of 3-acylpyrroles is the most general and advantageous method because it utilises easily accessible starting materials.In addition it is always regiospecific and readily provides 2,4-diacylpyrroles containing identical or different acyl groups in very high yields (81-100percent) under mild conditions, Alternative procedures concern the synthesis of precursors of 2,4-diacylpyrroles containing one or two acyl groups masked by a 1,3-benzodithiolyl or 1,3-benzoxathiolyl group and subsequent hydrolysis with HgO-35percent aq.HBF4-Me2SO.Overall yields are always good (52-60percent).Indirect acylation constitutes a secure complement to direct acylation when it is necessary to operate in the presence of protected acyl groups.