635680-22-7Relevant academic research and scientific papers
Analogs of M4 selective synthetic muscarinic receptor antagonists: Synthesis, binding and pharmacokinetic properties
Boehme, Thomas M.,Augelli-Szafran, Corinne E.,Hallak, Hussein,Schwarz, Roy D.
, p. 423 - 433 (2007/10/03)
Recently, highly selective M4 muscarinic receptor antagonists (e.g., PD 0320115) have been synthesized and pharmacologically characterized. One compound, PD 0298029 which was selected for in vivo testing, had low bioavailability (rat ~5%) and p
