635697-81-3

Upstream product

• 899797-70-7 2-(3-bromomethyl-2,4-dichlorobenzenesulfonylamino)-2-methylpropionic acid tert-butyl ester 
• 115310-98-0 8-hydroxy-2,4-dimethylquinoline 
• 899797-71-8 4-(3-hydroxyphenyl)pentan-2-one 
• 899797-69-4 2-(2,4-dichloro-3-methylbenzenesulfonylamino)-2-methylpropionic acid tert-butyl ester 
• 118-69-4 2,6-dichlorotoluene 
• 20511-03-9 4-(3’-hydroxyphenyl)-3(E)-buten-2-one 
• 69145-58-0 2,4-Dichloro-3-methylbenzenesulfonyl chloride 
• 100-83-4 meta-hydroxybenzaldehyde 
• 191614-96-7 4-(3-hydroxyphenyl)pentan-2-one O-(2,4-dinitrophenyl)oxime 

Relevant academic research and scientific papers

Design and synthesis of novel sulfonamide-containing bradykinin hB 2 receptor antagonists. 1. Synthesis and SAR of α,α- dimethylglycine sulfonamides

We recently published the extensive in vivo pharmacological characterization of MEN 16132 (J. Pharmacol. Exp. Ther. 2005, 616-623; Eur. J. Pharmacol. 2005, 528, 7), a member of the sulfonamide-containing human B 2 receptor (hB2R) ant

BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM

Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified,