635702-65-7

Upstream product

• 6269-91-6 4-nitrotoluene-2-sulfonamide 
• 635702-59-9 3-methyl-6-nitro-1H-indazole sulfate 
• 444731-75-3 N-(2-chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazole-6-amine 
• 6973-09-7 5-amino-2-methylbenzenesulfonamide 
• 444731-72-0 2,3-dimethyl-6-amino-2H-indazole 
• 444731-74-2 N-(2-chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine 
• 444731-73-1 2,3?dimethyl?6?nitro?2H?indazole 
• 6494-19-5 3-methyl-6-nitro-1H-indazole 
• 635702-64-6 pazopanib hydrochloride 
• 75-75-2 methanesulfonic acid 

Relevant academic research and scientific papers

CANCER TREATMENT METHOD

A method of treating cancer is described including administration of a pyrimidine derivative and a quinazoline derivative as well as a pharmaceutical composition including the same.

CHEMICAL PROCESS

A process for the preparation of pyrimidine derivatives, which are useful as VEGFR2 inhibitors is described herein. The described invention also includes pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.