635731-97-4

Usage

Uses

Used in Scientific Research and Development:
2-Bromo-4-hydroxynicotinonitrile is used as a chemical intermediate for [application reason] in the field of organic synthesis. It plays a crucial role in the synthesis of various organic compounds, contributing to the advancement of chemical research and the development of new materials and pharmaceuticals.
Used in Laboratory Settings:
2-Bromo-4-hydroxynicotinonitrile is used as a laboratory chemical for [application reason] in scientific research. It is essential for conducting experiments and testing hypotheses in the field of organic chemistry. Due to its potential to cause skin and eye irritation, it is crucial to handle and store 2-Bromo-4-hydroxynicotinonitrile correctly, using protective equipment and ensuring proper ventilation in the laboratory.

InChI:InChI=1/C6H3BrN2O/c7-6-4(3-8)5(10)1-2-9-6/h1-2H,(H,9,10)

Upstream product

• 98645-42-2 2-bromo-4-methoxypyridine-3-carbonitrile 
• 98645-43-3 2-chloro-3-cyano-4-methoxypyridine 
• 98645-45-5 2-Chlor-4-ethoxypyridin-3-carbonitril 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 5417-82-3 (1-ethoxyethylidene)malononitrile 
• 95689-38-6 1,1-dicyano-4-(N,N-dimethylamino)-2-methoxy-1,3-butadiene 

Downstream Products

• 635731-99-6 2-bromo-3-cyano-4-(4'-methoxybenzyloxy)pyridine 
• 635732-01-3 2-chloro-3-cyano-4-(4'-methoxybenzyloxy)pyridine 
• 635731-04-3 3-amino-4-(4-nitrophenylamino)thieno[2,3-b]pyridine-2-carboxylic acid amide 
• 635731-06-5 3-amino-4-(4-benzylpiperazin-1-yl)thieno[2,3-b]pyridine-2-carboxylic acid amide 
• 147992-83-4 3-amino-4-phenylaminothieno[2,3-b]pyridine-2-carboxylic acid amide 

Relevant academic research and scientific papers

ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF

The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists

SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste

SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES

Disclosed are compounds of formula (I), wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.