635731-97-4

Basic information

• Product Name: 2-BROMO-4-HYDROXYNICOTINONITRILE
• Synonyms: 2-BROMO-4-HYDROXYNICOTINONITRILE;3-Pyridinecarbonitrile, 2-broMo-4-hydroxy-
• CAS NO: 635731-97-4
• Molecular Formula: C₆H₃BrN₂O
• Molecular Weight: 199.00482
• Mol File: 635731-97-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 242.6 °C at 760 mmHg
• Flash Point: 100.5 °C
• Appearance: /
• Density: 1.84 g/cm³
• Vapor Pressure: 0.0337mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 2-BROMO-4-HYDROXYNICOTINONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-HYDROXYNICOTINONITRILE(635731-97-4)
• EPA Substance Registry System: 2-BROMO-4-HYDROXYNICOTINONITRILE(635731-97-4)

Safety Data

• Hazardous Substances Data: 635731-97-4(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-hydroxynicotinonitrile is a chemical compound with the molecular formula C6H3BrN2O. It is identified as an intermediate used in organic synthesis. This chemical is slightly soluble in water and has a brownish appearance. As a laboratory chemical, it's used primarily in scientific research and development activities. It is important to handle and store this compound correctly, as it can cause skin and eye irritation. It should always be used in well-ventilated environments and protective equipment should be worn when handling it. As with many chemicals, the impact of 2-Bromo-4-hydroxynicotinonitrile on the environment or health is not fully known, so it's essential to treat it as potentially harmful.

InChI:InChI=1/C6H3BrN2O/c7-6-4(3-8)5(10)1-2-9-6/h1-2H,(H,9,10)

Upstream product

• 98645-45-5 2-Chlor-4-ethoxypyridin-3-carbonitril 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 5417-82-3 (1-ethoxyethylidene)malononitrile 
• 95689-38-6 1,1-dicyano-4-(N,N-dimethylamino)-2-methoxy-1,3-butadiene 
• 98645-42-2 2-bromo-4-methoxypyridine-3-carbonitrile 
• 98645-43-3 2-chloro-3-cyano-4-methoxypyridine 

Downstream Products

• 635731-99-6 2-bromo-3-cyano-4-(4'-methoxybenzyloxy)pyridine 
• 635732-01-3 2-chloro-3-cyano-4-(4'-methoxybenzyloxy)pyridine 
• 147992-83-4 3-amino-4-phenylaminothieno[2,3-b]pyridine-2-carboxylic acid amide 
• 635731-06-5 3-amino-4-(4-benzylpiperazin-1-yl)thieno[2,3-b]pyridine-2-carboxylic acid amide 
• 635731-04-3 3-amino-4-(4-nitrophenylamino)thieno[2,3-b]pyridine-2-carboxylic acid amide 

Relevant articles and documents

ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF

The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.

SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES

Disclosed are compounds of formula (I), wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.