6362-87-4

Usage

Uses

Used in Organic Synthesis:
2-chloro-4-methyl-1,3,2-dioxaphosphinane serves as a reagent in organic synthesis, facilitating the creation of a range of other organic phosphorus compounds. Its unique structure allows it to act as an intermediate or a catalyst in various chemical reactions.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-chloro-4-methyl-1,3,2-dioxaphosphinane is utilized as a building block for the synthesis of complex molecules. Its incorporation into drug molecules can enhance their efficacy and pharmacological properties, contributing to the development of new medications.
Used in Agrochemical Production:
Similarly, in agrochemicals, 2-chloro-4-methyl-1,3,2-dioxaphosphinane is employed in the synthesis of pesticides and other crop protection agents. Its role in these products is crucial for improving the effectiveness of these chemicals in protecting crops from pests and diseases.
Used in Materials Science:
2-chloro-4-methyl-1,3,2-dioxaphosphinane also finds applications in the field of materials science, where it may be used to develop new materials with specific properties, such as flame retardants or polymers with unique characteristics.
Used in Drug Discovery:
In drug discovery, 2-chloro-4-methyl-1,3,2-dioxaphosphinane is explored for its potential to contribute to the development of new pharmaceutical agents. Its versatility in chemical reactions makes it a valuable tool in the synthesis of novel drug candidates.

Upstream product

• 18826-95-4 1.3-butanediol 
• 110-86-1 pyridine 
• 60-29-7 diethyl ether 
• 7719-12-2 phosphorus trichloride 
• 121-69-7 N,N-dimethyl-aniline 

Downstream Products

• 33892-95-4 4-methyl-2-methoxy-1,3,2-dioxaphosphorinane 
• 34875-40-6 (4-methyl-[1,3,2]dioxaphosphinan-2-yl)-phenyl-amine 
• 55549-69-4 4-methyl-2-phenylethynyl-[1,3,2]dioxaphosphinane 
• 60197-04-8 diphenylamide of 1,3-butylenecyclophosphorous acid 
• 51908-91-9 S-Benzyl-O,O-(1-methyltrimethylen)phosphorothioit 
• 21990-37-4 N-(4-methyl-[1,3,2]dioxaphosphinan-2-yl)-N'-phenyl-hydrazine 
• 5578-05-2 2-(3-chloro-1-methyl-propoxy)-5-methyl-3-phenyl-2,3-dihydro-[1,2]oxaphosphole 2-oxide 
• 5578-12-1 1-(3-Chlor-1-methyl-propoxy)-2,2,5,5-tetramethyl-1-oxo-2,5-dihydro-<1λ⁵,3,4>phosphadiazol 
• 139444-79-4 2-trimethylhydrazino-4-methyl-1,3,2-dioxaphosphorinane 
• 87514-44-1 N⁶-(4-methyl-1,3,2-dioxaphosphorinan-2-yl)-3-(α-methylphenethyl)sydnone imine 
• 122058-72-4 2-N,N-ethylphenylamino-4-methyl-1,3,2-dioxaphosphorinane 
• 81637-93-6 N⁶-(4'-methyl-1',3',2'-dioxaphosphorinano)-3-cumylsydnone imine 
• 86266-43-5 1-methyltrimethylene N-p-tolyl-N-(2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl)amidophosphite 
• 16368-20-0 4-methyl-[1,3,2]dioxaphosphinane 2-oxide 

Relevant academic research and scientific papers

Hydroxyferrocene as a prochiral analog of phenols: cyclopalladation of a mixed phosphite ester of hydroxyferrocene

Hydroxyferrocene (ferrocenol), a metallocene analog of phenol, has been converted into a phosphite ester with chiral (racemic) butane-1,3-diol which undergoes cyclopalladation similarly to hydroxyarene phosphites. In this case, a planar chirality emerges

Synthesis and Isomer Composition of 2-Polyfluoroalkoxy-1,3,2-dioxaphospholanes and -phosphinanes

Polyfluoroalkanols readily reacted with 2-chloro-1,3,2-dioxaphospholanes and 2-chloro-1,3,2-dioxaphosphinanes in hexane in the presence of triethylamine (–10 to 25°C, 5 h) to give 2-polyfluoroalkoxy-1,3,2- dioxaphospholanes and 2-polyfluoroalkoxy-1,3,2-dioxaphosphinanes in 48–72% yield. The products were found to exist as mixtures of cis and trans isomers with the trans isomer predominating for the phospholanes and cis isomer predominating for the phosphinanes according to the 1H, 13C, 19F, and 31P NMR data.

Phosphosulfonate herbicides

This invention pertains to phosphosulfonates, having the general formula STR1 wherein Y is phenyl, naphthyl, benzyl, a (C5 -C8)cycloalkyl, a 5-membered heteroaromatic ring, a 6-membered heteraromatic ring, a fused 5,6-membered heteroaromatic ring, or a fused 6,6-membered heteroaromatic ring; and X is oxygen or sulfur; and R1 and R2 are each independently selected from substituted or unsubstituted alkyl, alkoxy, alkylthio, alkenyloxy, alkynyloxy, haloalkoxy, cyanoalkoxy, alkoxyalkoxy, cycloalkyloxy, cycloalkylalkoxy, alkylideneiminooxy, chloro, amino, phenyl or phenoxy; or R1 and R2 are both alkoxy, taken together with the phosphorus atom to form a 6-membered oxygen-containing ring; compositions containing these compounds and their use as herbicides.

Synthesis and Conformational Analysis of Six-Membered Cyclic Phenyl Phosphites

A procedure for synthesizing potentially anancomeric equatorial phenyl phosphites (cis-1 and eq-cis-2) is reported.Spectral characteristics and low-temperature NMR studies on the phenyl phosphites suggest that eq-cis-2 is a system with a predominant chair conformation in solution.On the contrary, cis-1 is conformationally heterogeneous.