63756-58-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-3-ethoxypyridine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs, enhancing the therapeutic potential of existing medications.
Used in Agricultural Chemicals Industry:
2-Chloro-3-ethoxypyridine is used as a precursor in the production of insecticides, herbicides, and fungicides, due to its reactivity and potential to form active ingredients that protect crops from pests and diseases.
It is important to handle 2-Chloro-3-ethoxypyridine with care, as it is classified as a hazardous material that can cause skin and eye irritation upon contact, necessitating proper safety measures during its use and storage.

Upstream product

• 6636-78-8 2-chloro-3-hydroxypyridine 
• 75-03-6 ethyl iodide 
• 16867-04-2 dihydroxypyridine 
• 74-96-4 ethyl bromide 
• 909854-16-6 3-ethoxypyridin-2-ol 

Downstream Products

• 927396-09-6 3-ethoxy-2-phenylpyridine 

Relevant academic research and scientific papers

AMINOPYRAZINE COMPOUNDS AS HPK1 INHIBITOR AND THE USE THEREOF

Disclosed herein is an aminopyrazine compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating HPK1 related disorders or diseases by using the compound disclosed herein.

NOVEL ISOINDOLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

Disclosed are a novel isoindoline derivative, a pharmaceutical composition and use thereof. The compound of formula I, or the pharmaceutically acceptable salt, solvate, polymorph, co-crystal, stereoisomer, isotopic compound, metabolite or prodrug thereof disclosed in the invention can regulate the generation and/or activity of PDE4 and/or TNF-α so as to effectively treat cancer and inflammatory diseases.

BENZOPIPERIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND HEMOGLOBINOPATHIES

A compound of formula I: (I) wherein: n is 1 or 2; p is 0 or 1; R1a, R1b, R1c and R1d are independently selected from H, halo, C1-4 alkyl, C1-4 fluoroalkyl, C3-4 cycloalkyl, C1-4 alkyloxy, NH-C1-4 alkyl and cyano; R2a and R2b are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R2c and R2d are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R2e is H or Me; R3a and R3b are independently selected from H and Me; R4 is either H or Me; R5 is either H or Me; R6a and R6b are independently selected from H and Me; A is either (IIa), where R7a is selected from N-linked N-containing C5-7 heterocycyl and (A); or (ii) (IIb), where X is selected from CH2, N H and O, one of R8a and R8b is selected from CI and ethoxy and the other of R8a and R8b is H.

Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives

This invention is concerned with compounds of the formula wherein A, B1, B2, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.