63791-11-7

Upstream product

• 130602-09-4 6-phenylhex-5-yn-1-al 
• 125536-51-8 (Z)-1-tert-butyldimethylsilyloxy-2-phenylmethylenecyclopentane 
• 29329-03-1 5-hexynal 
• 1078-58-6 diphenylzinc 
• 190258-39-0 1-Phenyl-6-<(tetrahydro-2H-pyran-2-yl)oxy>-1-hexyn-3-ol 
• 173728-39-7 tert-butyl-<1-(3-iodopropyl)-3-phenylprop-2-ynyloxy>dimethylsilane 
• 190258-65-2 tert-butyldimethyl-{3-phenyl-1-[3-(tetrahydropyran-2-yloxy)propyl]-1-prop-2-ynyloxy}silane 

Downstream Products

• 135357-02-7 (-)-(1R,2S)-2-benzylcyclopentanol 
• 135357-08-3 trans-2-Benzylcyclopentanol 
• 13694-31-0 (1SR,2SR)-α-benzylcyclopentanol 
• 13694-31-0 (1SR,2RS)-α-benzylcyclopentanol 

Relevant academic research and scientific papers

Stereoselective hydrogen transfer reactions of vinyl radicals: Cyclization of alkynyl iodides by unimolecular chain transfer from silicon hydrides

The cyclization of several substituted hexynyl and heptynyl iodides proceeds stereoselectively to give either E- or Z-exocyclic double bonds depending on the type of precursor and radical chain used, In UniMolecular Chain Transfer (UMCT) reactions, the intramolecular abstraction of hydrogen by the intermediate vinyl radical leads exclusively to the E-isomer while the traditional tin hydride method usually provides the Z-isomer with good selectivity.

Intramolecular reductive cyclization of aldehydes and ketones with alkynes promoted by samarium(II) iodide

Samarium(II) iodide mediated intramolecular reductive coupling of carbonyl groups and alkynes in the presence of HMPA and t-BuOH was successfully performed to provide cyclized products. Some cyclic compounds containing a heteroatom such as oxygen or nitrogen were also efficiently prepared by this coupling reaction.