640272-65-7Relevant academic research and scientific papers
Reactions of Isocyanates with Methyl N-(Cyanothioformyl)anthranilate
Deck,Papadopoulos,Smith
, p. 885 - 893 (2007/10/03)
The triethylamine-catalyzed reactions of methyl N-(cyanothioformyl)anthranilate (1) with isocyanates result in cyclization involving the cyano group to form methyl 2-(4-imino-2-oxo-3-substituted-5-thioxoimidazolidin-1-yl)benzoates (4). Ring closure at the ester carbonyl to form 3-aryl-3,4-dihydro-4-oxoquinazoline-2-carbonitriles (8) is observed when the S-methyl derivative of 1 is allowed to react with aromatic amines.
