64066-71-3

Upstream product

• 72789-82-3 (+/-)-4β-(2',2'-dimethoxyethyl)-3α-((1'R*)-p-nitrobenzyloxycarbonyloxyethyl)-2-azetidinone 
• 72447-84-8 methyl 3-amino-5-hydroxy-1,1-dimethoxyhexane-4-carboxylate 
• 72447-85-9 trans-4-<(2',2'-dimethoxy)ethyl>-3-<(1'R)-hydroxyethyl>azetidin-2-one 
• 72447-82-6 trans-4-methoxycarbonyl-3-(2',2'-dimethoxyethyl)-5-methylisoxazoline 
• 72789-82-3 (3S,4R)-4-(2,2-dimethoxyethyl)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-2-oxoazetidine 

Downstream Products

• 64066-69-9 (3S,4R)-4-(2-hydroxyethyl)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)-ethyl]-2-oxoazetidine 
• 76347-45-0 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-(3-p-nitrobenzyloxycarbonyl-2-oxopropyl)azetidin-2-one 
• 76335-78-9 (+/-)-p-nitrobenzyl 6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-3,7-dioxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 78072-36-3 (5R,6S)-3-(Diphenoxy-phosphoryloxy)-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 78072-35-2 (+/-)-p-nitrobenzyl 6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-3-phenylthio-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 78072-32-9 (+/-)-4α-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3β-<(1R^*)-1(p-nitrobenzyloxycarbonyloxy)ethyl>-1-azetidin-2-one 
• 78072-31-8 Hydroxy-{(2R,3S)-2-[2-(4-nitro-benzyloxycarbonylamino)-ethylsulfanylcarbonylmethyl]-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 78072-34-1 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-1--4β-<(phenylthio)carbonylmethyl>azetidin-2-one 
• 78072-37-4 Hydroxy-{(3S,4R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-2-oxo-4-phenylsulfanylcarbonylmethyl-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 78072-30-7 (+/-)-4β-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 78072-33-0 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-<(phenylthio)carbonylmethyl>azetidin-2-one 
• 65991-26-6 (+/-)-p-nitrobenzyl 3-<2-(p-nitrobenzyloxycarbonylamino)ethylthio>-6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 76335-76-7 (+/-)-4β-carboxymethyl-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 65794-47-0 (+/-)-4β-(2'-hydroxyethyl)-3α-((1'R*)-p-nitrobenzyloxycarbonyloxyethyl)-2-azetidinone 

Relevant academic research and scientific papers

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof

This invention relates to novel 4-substituted-2-oxoazetidine compounds and salts thereof, which are useful intermediates in the preparation of antibiotics having the fundamental skeleton of Thienamycin, which compounds are of the formula: STR1 in which R

Studies on the Syntheses of Heterocyclic Compounds. Part 877. An Alternative Synthesis of Protected (+/-)-Thienamycin and a Related Compound

An alternative total synthesis of protected (+/-)-thienamycin (2) and an analogue is described. (+/-)-4β-(2,2-Dimethoxyethyl)-3α-*)-1-(-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one (5), prepared from isoxazoline derivatives (4), was conve

Studies on the Syntheses of Heterocyclic Compounds. 800. A Formal Total Synthesis of (+/-)-Thienamycin and (+/-)-Decysteaminylthienamycin Derivative

The synthesis of a key intermediate for the preparation of (+/-)-thienamycin (1) and its derivatives has been developed.By 1,3-dipolar cycloaddition, the nitrile oxide derived from 3-nitropropanal dimethyl acetal (3) was added to methyl crotonate to give

AN ALTERNATIVE TOTAL SYNTHESIS OF (+/-)-THIENAMYCIN

(+/-)-4β-(2',2'-Dimethoxyethyl)-3α-(1'R*)-p-nitrobenzylocarbonyloxyethyl)-2-azetidinone (4) was converted into the thienamycin derivative (2) protected with p-nitrobenzyl group, utilizing the carbene insertion reaction and subsequent introduction of the c