72789-82-3

Upstream product

• 67-56-1 methanol 
• 80527-88-4 methyl 3-methyl-2-[(3S,4R)-3-{(1S)-1-(p-nitrobenzyloxycarbonyloxy)ethyl}-2-oxo-4-allylazetidin-1-yl]but-2-enoate 
• 74614-77-0 (3S,4R)-3-(1-hidroxyethyl)-1-(1-methoxycarbonyl-2-methyl-1-propenyl)-4-methylthio-2-azetidinone 
• 76855-55-5 methyl 3-methyl-2-[(3S,4R)-4-methylthio-3-{(1S)-1-(p-nitrobenzyloxycarbonyloxy)ethyl}-2-oxoazetidin-1-yl]-but-2-enoate 
• 72447-81-5 3-Nitropropanal dimethyl acetal 
• 80559-31-5 methyl 3-methyl-2-[(3S,4R)-3-[(1R)-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-2-oxo-4-allylazetidin-1-yl]but-2-enoate 
• 72447-84-8 methyl 3-amino-5-hydroxy-1,1-dimethoxyhexane-4-carboxylate 
• 81038-18-8 3,3-Dimethoxy-propionitrile N-oxide 
• 72447-85-9 trans-4-<(2',2'-dimethoxy)ethyl>-3-<(1'R)-hydroxyethyl>azetidin-2-one 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 72496-42-5 4-(2,2-Dimethoxy-ethyl)-3-(1-hydroxy-ethyl)-azetidin-2-one 
• 72447-82-6 trans-4-methoxycarbonyl-3-(2',2'-dimethoxyethyl)-5-methylisoxazoline 
• 73844-78-7 trans-3-(2',2'-dimethoxyethyl)-5-methylisoxazoline-4-carboxylic acid 
• 78522-77-7 (S)-3-Amino-2-((R)-1-hydroxy-ethyl)-5,5-dimethoxy-pentanoic acid 

Downstream Products

• 64066-71-3 (3S,4R)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-4-(2-oxoethyl)-2-oxoazetidine 
• 65991-26-6 (+/-)-p-nitrobenzyl 3-<2-(p-nitrobenzyloxycarbonylamino)ethylthio>-6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 78072-33-0 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-<(phenylthio)carbonylmethyl>azetidin-2-one 
• 78072-30-7 (+/-)-4β-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 78072-37-4 Hydroxy-{(3S,4R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-2-oxo-4-phenylsulfanylcarbonylmethyl-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 78072-34-1 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-1--4β-<(phenylthio)carbonylmethyl>azetidin-2-one 
• 78072-31-8 Hydroxy-{(2R,3S)-2-[2-(4-nitro-benzyloxycarbonylamino)-ethylsulfanylcarbonylmethyl]-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 78072-32-9 (+/-)-4α-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3β-<(1R^*)-1(p-nitrobenzyloxycarbonyloxy)ethyl>-1-azetidin-2-one 
• 78072-36-3 (5R,6S)-3-(Diphenoxy-phosphoryloxy)-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 76335-76-7 (+/-)-4β-carboxymethyl-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 76335-78-9 (+/-)-p-nitrobenzyl 6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-3,7-dioxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 76347-45-0 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-(3-p-nitrobenzyloxycarbonyl-2-oxopropyl)azetidin-2-one 
• 73844-79-8 (+/-)-4β-(2',2'-trimethylenedithioethyl)-3α-((1'-S*)-p-nitrobenzyloxycarbonyloxyethyl)-2-azetidinone 
• 72778-03-1 Carbonic acid 4-nitro-benzyl ester 1-[(3R,4S)-2-oxo-4-(2-oxo-ethyl)-azetidin-3-yl]-ethyl ester 

Relevant academic research and scientific papers

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof

This invention relates to novel 4-substituted-2-oxoazetidine compounds and salts thereof, which are useful intermediates in the preparation of antibiotics having the fundamental skeleton of Thienamycin, which compounds are of the formula: STR1 in which R

STEREO- AND REGIOSPECIFIC ALLYLATION OF 4-CHLOROAZETIDINONES WITH ALLYLSILANES: CONVERGENT SYNTHESIS OF A KEY INTERMEDIATE FOR (+)-THIENAMYCIN

An efficient stereospecific synthesis of optically active 4-allylazetidinones (6, 7, 11, and 15a,b) has been accomplished using silver-promoted coupling reaction of allylsilanes (5 and 14b) with 4-chloroazetidinones (3, 4, and 10a,b) derived from penicillins.

An Asymmetric Synthesis of Synthetic Intermediates to Thienamycin and Epithienamycins A and B

An asymmetric synthesis for the synthetic intermediates to carbapenem antibiotics was examined via isoxazoline derivatives prepared by 1,3-dipolar cycloaddition between the nitrile oxide and menthyl crotonate.The (4S)-trans-azetidinone (14) having the ant

Studies on the Syntheses of Heterocyclic Compounds. 800. A Formal Total Synthesis of (+/-)-Thienamycin and (+/-)-Decysteaminylthienamycin Derivative

The synthesis of a key intermediate for the preparation of (+/-)-thienamycin (1) and its derivatives has been developed.By 1,3-dipolar cycloaddition, the nitrile oxide derived from 3-nitropropanal dimethyl acetal (3) was added to methyl crotonate to give