6407-36-9Relevant academic research and scientific papers
Novel anti-tuberculosis agents from MCR libraries
Doemling, Alexander,Achatz, Sepp,Beck, Barbara
, p. 5483 - 5486 (2008/02/12)
Structure-based design of libraries of multi-component reaction products yields novel potent anti-tuberculosis compounds. Synthesis and preliminary biological results are presented.
Transformation of presumptive precursors to frontalin and ex-brevicomin by bark beetles and the West Indian sugarcane weevil (Coleoptera)
Perez,Gries,Gries,Oehlschlager
, p. 445 - 450 (2007/10/03)
(Z)-6-Nonen-2-one (1) has recently been shown to be the biosynthetic precursor for the aggregation pheromone exo-brevicomin (2) in mountain pine beetle (MPB) males, Dendroctonus ponderosae (Hopkins). We tested the hypotheses that (1) 6-methyl-6-hepten-2-one (3) is the biosynthetic precursor for the aggregation pheromone frontalin (4) in the spruce beetle (SB), Dendroctonus rufipennis (Kirby), and (2) that frontalin and exo-brevicomin are produced from 3 and 1, respectively, only by beetles that utilize them as aggregation pheromones. Exposure of scolytids MPB, SB, pine engraver (PE), Ips pini (Say) and Ips tridens (Mannerheim) and West Indian sugar cane weevil (WISW), Metamasius hemipterus sericeus (Olivier) to deuterio- or protio-3 invariably resulted in the production of deuterio- or protio-4. Similarly, exposure of SB, WISW and I. tridens to 1 resulted in the production of 2. We were unable to demonstrate the presence of 3 in SB volatiles, nor were we able to demonstrate the conversion of 6-methyl-5-hepten-2-one to 3 by SB. Production of enantiomerically enriched frontalin and exo-brevicomin by all the beetles exposed to respective precursors reveals widespread occurrence of nonspecific polysubstrate monooxidases in the Coleoptera.
A simple and inexpensive method for the preparation of imines and azadienes
Saoudi,Benguedach,Benhaoua
, p. 2349 - 2354 (2007/10/02)
A number of imines and azadienes were prepared in high yield and good purity by using the condensation reactions of various aldehydes and ketones with amines over natural Algerian bentonite.
HOMOLYTIC ADDITION OF 1,4-DIOXANE TO SCHIFF BASES
Pastushenko, E. V.,Safiulova, G. I.,Kruglov, D. E.
, p. 2143 - 2148 (2007/10/02)
Radical addition of 1,4-dioxane to aldimines proceeds at the imidyl carbon atom with formation of asymmetrical secondary amines.By the method of competitive kinetics we have determined the relative activities of Schiff bases and have found that the regiod
Imine-Enamine Tautumerism - Nucleophilic Reactions of Imines
Atta-ur-Rahman,Ahmad, Viqar Uddin,Sultana, Mumtaz,Perveen, Nusrat,Sultana, Nighat
, p. 757 - 761 (2007/10/02)
A reinvestigation of the reactivity of N-isopropylidene cyclohexylamine to methyl acrylate by GC-MS analysis has shown that the major product is the β-aminoester (9) formed by the N-alkylation of cyclohexylamine which may be generated by a dimerisation-elimination sequence.A number of other products resulting from N- and C-alkylation of the ketimine have been identified. - Key words: Enamines, Ketimines, Nucleophiles, Alkylation
