640735-24-6

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]-;4-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine;4-Bromo-1-(triisopropylsilyl)-7-azaindole;(4-Bromopyrrolo[2,3-b]pyridin-1-yl)-triisopropyl-silane
• CAS NO: 640735-24-6
• Molecular Formula: C₁₆H₂₅BrN₂Si
• Molecular Weight: 353.39
• Mol File: 640735-24-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 343.363°C at 760 mmHg
• Flash Point: 161.461°C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.548
• PKA: 4.43±0.30(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]-(640735-24-6)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]-(640735-24-6)

Safety Data

• Hazardous Substances Data: 640735-24-6(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]- is a chemical compound with the molecular formula C14H22BrNSi. It is a brominated derivative of 1H-pyrrolo[2,3-b]pyridine, with a tris(1-methylethyl)silyl group attached to the nitrogen atom. 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]- is commonly used in organic synthesis and medicinal chemistry research, as well as in the development of pharmaceutical compounds. The tris(1-methylethyl)silyl group serves as a protective group for the amine functionality, allowing for selective reactions at other functional groups in the molecule. 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[tris(1-methylethyl)silyl]- may also have potential applications in the development of new materials or as a building block for the synthesis of other complex organic molecules.

InChI:InChI=1/C16H25BrN2Si/c1-11(2)20(12(3)4,13(5)6)19-10-8-14-15(17)7-9-18-16(14)19/h7-13H,1-6H3

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 271-63-6 7-Azaindole 
• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 
• 348640-06-2 4-bromo-7-azaindole 

Downstream Products

• 685513-89-7 4,5-difluoro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine 
• 1172068-36-8 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-ylamine 
• 1190317-94-2 5-chloro-4-fluoro-1H-pyrrolo[2,3-b]pyridine 
• 1196507-66-0 4,5-difluoro-1H-pyrrolo[2,3-b]pyridine 
• 1190699-11-6 (1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)boronic acid 
• 1196508-42-5 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methoxybenzamide trifluoroacetate 
• 1196505-03-9 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-chloro-4-fluorobenzamide hydrochloride 
• 1196504-51-4 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-fluorobenzamide hydrochloride 
• 1196504-67-2 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methoxybenzamide hydrochloride 
• 1196504-40-1 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methylbenzamide hydrochloride 
• 1196504-96-7 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclobutanecarboxamide hydrochloride 

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