64075-37-2

Basic information

• Product Name: N-(2-methylpropyl)hexanamide
• CAS NO: 64075-37-2
• Molecular Formula: C₁₀H₂₁NO
• Molecular Weight: 171.2798
• Mol File: 64075-37-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 251.4°C at 760 mmHg
• Flash Point: 144.7°C
• Density: 0.856g/cm³
• Vapor Pressure: 0.0205mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: N-(2-methylpropyl)hexanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methylpropyl)hexanamide(64075-37-2)
• EPA Substance Registry System: N-(2-methylpropyl)hexanamide(64075-37-2)

Safety Data

• Hazardous Substances Data: 64075-37-2(Hazardous Substances Data)

Usage

General Description

N-(2-methylpropyl)hexanamide is a chemical compound with the molecular formula C11H23NO. It is also known as isobutylhexanamide and is classified as an amide. N-(2-methylpropyl)hexanamide is commonly used in the manufacturing of various products, including pharmaceuticals, pesticides, and as a flavoring agent in food. It is a colorless liquid with a slightly unpleasant odor. N-(2-methylpropyl)hexanamide is flammable and may cause irritation to the skin and eyes upon contact, and inhalation or ingestion may lead to potential health hazards.

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Relevant articles and documents

New lead discovery of herbicide safener for metolachlor based on a scaffold-hopping strategy

The use of herbicide safeners can significantly alleviate herbicide injury to protect crop plants and expand the application scope of the existing herbicides in the field. Sanshools, which are well known as spices, are N-alkyl substituted compounds extracted from the Zanthoxylum species and have several essential physiological and pharmacological functions. Sanshools display excellent safener activity for the herbicide metolachlor in rice seedlings. However, the high cost of sanshools extraction and difficulties in the synthesis of their complicated chemical structures limit their utilization in agricultural fields. Thus, the present study designed and synthesized various N-alkyl amide derivatives via the scaffold-hopping strategy to solve the challenge of complicated structures and find novel potential safeners for the herbicide metolachlor. In total, 33 N-alkyl amide derivatives (2a–k, 3a–k, and 4a–k) were synthesized using amines and saturated and unsaturated fatty acids as starting materials through acylation and condensation. The identity of all the target compounds was well confirmed by1H-NMR,13C-NMR, and high-resolution mass spectrometry (HRMS). The primary evaluation of safener activities for the compounds by the agar method indicated that most of the target compounds could protect rice seedlings from injury caused by metolachlor. Notably, compounds 2k and 4k displayed excellent herbicide safener activities on plant height and demonstrated relatively similar activities to the commercialized compound dichlormid. Moreover, we showed that compounds 2k and 4k had higher glutathione S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and polyphenol oxidase (PPO) activities in rice seedlings, compared to the metolachlor treatment. In particular, 2k and 4k are safer for aquatic organisms than dichlormid. Results from the current work exhibit that compounds 2k and 4k have excellent crop safener activities toward rice and can, thus, be promising candidates for further structural optimization in rice protection.

Enzymatic Method for N-Acyl Homoserine Lactones Synthesis Using Immobilized Candida antarctica Lipase

Abstract: An enzymatic method to produce N-acyl homoserine lactones (AHLs) is described. This report represents the first example of the synthesis of bioactive AHLs using immobilized Candida antarctica lipase as the catalyst. The reaction yields, evaluate

Intermolecular hydrogen bonding between N-substituted caproamides and tetrahydrofuran

The results are reported of a study of hydrogen bonding between various N-substituted caproamides and tetrahydrofuran as an O-electron donor by means of FTIR spectroscopy. The spectroscopic characteristics for N-H.O hydrogen bonded complexes are given. The B3LYP functional with 6-31G**basis set has been used to calculate the structural parameters of the studied hydrogen bonded complexes. It can be assumed that both inductive and steric effects play an important role in the stability of these hydrogen bonded complexes.